SCHEMBL8974606

SCHEMBL8974606

CC[Si](Cl)(OC(C)=O)OC(C)=O

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.38
LMNA P02545 1/20 0.38
HSD17B10 Q99714 1/20 0.38
TSHR P16473 2/20 0.32
CA4 P22748 2/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2685728 0.79
SCHEMBL27981635 0.73 ALDH1A1 (0.33) ALDH1A1LMNAHSD17B10
SCHEMBL476015 0.72 ALDH1A1 (0.41) ALDH1A1LMNAHSD17B10TSHRTDP1
SCHEMBL131295 0.72 ALDH1A1 (0.41) ALDH1A1LMNAHSD17B10TSHRTDP1
SCHEMBL133195 0.72 ALDH1A1 (0.41) ALDH1A1LMNAHSD17B10TSHRTDP1
SCHEMBL9722203 0.72 ALDH1A1 (0.31) ALDH1A1
SCHEMBL10773422 0.71 ALDH1A1 (0.39) ALDH1A1LMNAHSD17B10TSHRCA4
SCHEMBL7761298 0.71
SCHEMBL10777409 0.71 ALDH1A1 (0.39) ALDH1A1LMNAHSD17B10TSHRCA4
SCHEMBL3791516 0.70 ALDH1A1 (0.39) ALDH1A1LMNAHSD17B10TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0509213-B1 Process for the simultaneous and continuous production of carbonyloxy silanes and of carboxylic acid chlorides HUELS CHEMISCHE WERKE AG (DE) 1996-04-10 EP disclosed
EP-0509213-A1 Process for the simultaneous and continuous production of carbonyloxy silanes and of carboxylic acid chlorides HÜLS AKTIENGESELLSCHAFT (DE) 1992-10-21 EP disclosed