SCHEMBL476015

SCHEMBL476015

CC[Si](CC)(CC)OC(C)=O

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.41
LMNA P02545 2/20 0.41
HSD17B10 Q99714 1/20 0.41
TSHR P16473 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
ALOX15 P16050 2/20 0.33
BLM P54132 1/20 0.32
PMP22 Q01453 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ether SCHEMBL10866831 0.90 ALDH1A1 (0.43) ALDH1A1LMNAHSD17B10TSHRALOX15
SCHEMBL706665 0.89 ALDH1A1 (0.38) ALDH1A1LMNAHSD17B10TSHRTDP1
SCHEMBL707081 0.89 ALDH1A1 (0.38) ALDH1A1LMNAHSD17B10TSHRTDP1
SCHEMBL706824 0.85 ALDH1A1 (0.35) ALDH1A1LMNAHSD17B10
SCHEMBL705769 0.85 ALDH1A1 (0.35) ALDH1A1LMNAHSD17B10
SCHEMBL12898556 0.81 ALDH1A1 (0.32) ALDH1A1LMNAHSD17B10
SCHEMBL12898580 0.79 ALDH1A1 (0.31) ALDH1A1LMNAHSD17B10
SCHEMBL5561661 0.79 ALDH1A1 (0.38) ALDH1A1LMNAHSD17B10TDP1ALOX15
SCHEMBL476034 0.78 ALDH1A1 (0.38) ALDH1A1LMNAHSD17B10TSHRTDP1
SCHEMBL22557964 0.77 FFAR3 (0.35) ALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 353 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11769871-B2 Lithium secondary batteries and nonaqueous electrolyte for use in the same MITSUBISHI CHEMICAL CORPORATION (JP) 2023-09-26 US claimed
US-20220280699-A1 NANOCOATINGS AND METHODS FOR FABRICATING AN INTRACARDIAC ECHOCARDIOGRAPHY ULTRASOUND TRANSDUCER ST. JUDE MEDICAL, CARDIOLOGY DIVISION, INC. 2022-09-08 US claimed
US-10991571-B2 High temperature atomic layer deposition of silicon oxide thin films VERSUM MATERIALS US, LLC (US) 2021-04-27 US claimed
US-20210066707-A1 LITHIUM SECONDARY BATTERIES AND NONAQUEOUS ELECTROLYTE FOR USE IN THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2021-03-04 US claimed
US-20190189431-A1 High Temperature Atomic Layer Deposition of Silicon Oxide Thin Films VERSUM MATERIALS US, LLC (US) 2019-06-20 US claimed
US-20170256399-A9 High Temperature Atomic Layer Deposition Of Silicon Oxide Thin Films AIR PRODUCTS AND CHEMICALS, INC. (US) 2017-09-07 US claimed
US-20160365244-A1 High Temperature Atomic Layer Deposition Of Silicon Oxide Thin Films AIR PRODUCTS AND CHEMICALS, INC. (US) 2016-12-15 US claimed
US-20130295779-A1 HIGH TEMPERATURE ATOMIC LAYER DEPOSITION OF SILICON OXIDE THIN FILMS VERSUM MATERIALS US, LLC 2013-11-07 US claimed
EP-2650399-A2 High temperature atomic layer deposition of silicon oxide thin films AIR PRODUCTS AND CHEMICALS, INC. (US) 2013-10-16 EP claimed
US-8148446-B2 Silyl esters, their use in binder systems and paint compositions and a process of production thereof SIGMAKALON B.V. (NL) 2012-04-03 US claimed
EP-1462472-A1 A process for the protection of acid groups in polymers Sigma Kalon Services B.V. (NL) 2004-09-29 EP claimed
EP-1462467-A1 A process for the production of silyl group containing polymer resin Sigma Kalon Services B.V. (NL) 2004-09-29 EP claimed
EP-1436018-A1 NITRIC OXIDE-RELEASING COATED MEDICAL DEVICES AND METHOD OF PREPARING SAME THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2004-07-14 EP claimed
WO-2004056837-A1 PROCESS FOR THE PRODUCTION OF HYDROCARBYL SILYL CARBOXYLATE COMPOUNDS SIGMA COATINGS B.V. (NL) 2004-07-08 WO claimed
EP-1432857-A1 COATED OPTICAL FIBERS USING ADHESION PROMOTERS, AND METHODS FOR MAKING AND USING SAME BORDEN CHEMICAL, INC. (US) 2004-06-30 EP claimed
US-20030129397-A1 Coated optical fibers using adhesion promoters, and methods for making and using same HEXION INC. 2003-07-10 US claimed
WO-2003026717-A1 NITRIC OXIDE-RELEASING COATED MEDICAL DEVICES AND METHOD OF PREPARING SAME THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2003-04-03 WO claimed
WO-2003023101-A1 COATED OPTICAL FIBERS USING ADHESION PROMOTERS, AND METHODS FOR MAKING AND USING SAME BORDEN CHEMICAL, INC. (US) 2003-03-20 WO claimed
US-4135045-A PROCESS FOR POLYMERIZATION OF OLEFINS AND CATALYST COMPOSITION THEREFOR MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1979-01-16 US claimed
US-4048415-A TITANIUM-ALUMINUM COORDINATION CATALYSTS MITSUI PETROCHEMICAL INDUSTRIES LTD. (JA) 1977-09-13 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190189431-A1 High Temperature Atomic Layer Deposition of Silicon Oxide Thin Films VIM, CDH1, ALDOA ALDH1A1 633/4885LMNA 495/4885HSD17B10 841/4885
US-10991571-B2 High temperature atomic layer deposition of silicon oxide thin films VIM, CDH1, ALDOA ALDH1A1 633/4885LMNA 495/4885HSD17B10 841/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.