Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 10/20 | 0.50 |
| ▸ | PPARG | P37231 | 9/20 | 0.50 |
| ▸ | PPARA | Q07869 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8974677 | 0.89 | PPARG (0.57) | FFAR1PPARGPPARAMEN1ALDH1A1 | |
| SCHEMBL8974649 | 0.87 | FFAR1 (0.53) | FFAR1PPARGPPARAMEN1ALDH1A1 | |
| SCHEMBL8974734 | 0.86 | FFAR1 (0.56) | FFAR1PPARGPPARA | |
| SCHEMBL8975130 | 0.85 | FFAR1 (0.52) | FFAR1PPARGPPARA | |
| SCHEMBL8975446 | 0.83 | PPARG (0.50) | FFAR1PPARGPPARA | |
| SCHEMBL8974550 | 0.83 | FFAR1 (0.52) | FFAR1PPARGMEN1ALDH1A1CYP3A4 | |
| SCHEMBL8974743 | 0.82 | FFAR1 (0.59) | FFAR1PPARGPPARAMEN1ALDH1A1 | |
| SCHEMBL8975029 | 0.82 | FFAR1 (0.50) | FFAR1PPARGMEN1ALDH1A1CYP3A4 | |
| SCHEMBL8974598 | 0.81 | FFAR1 (0.49) | FFAR1PPARGMEN1ALDH1A1CYP3A4 | |
| SCHEMBL8974608 | 0.81 | FFAR1 (0.54) | FFAR1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578620-A | TREATMENT OF DIABETES AND HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 1996-11-26 | — | — | US | disclosed |
| EP-0678511-A2 | Thiazolidine and oxazolidine derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1995-10-25 | — | — | EP | disclosed |