SCHEMBL8974734

SCHEMBL8974734

CC(COc1ccc(CC2SC(=O)NC2=O)cc1)NCC(O)COc1ccc(-c2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 10/20 0.56
PPARG P37231 8/20 0.52
PPARA Q07869 2/20 0.47
ADRB2 P07550 1/20 0.47
ADRB1 P08588 1/20 0.47
ADRB3 P13945 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8974677 0.95 PPARG (0.57) FFAR1PPARGPPARAADRB2ADRB1
SCHEMBL8974743 0.94 FFAR1 (0.59) FFAR1PPARGPPARA
SCHEMBL8974649 0.90 FFAR1 (0.53) FFAR1PPARGPPARA
SCHEMBL8975130 0.89 FFAR1 (0.52) FFAR1PPARGPPARA
SCHEMBL8974550 0.87 FFAR1 (0.52) FFAR1PPARG
SCHEMBL8974731 0.86 FFAR1 (0.50) FFAR1PPARGPPARA
SCHEMBL8975029 0.86 FFAR1 (0.50) FFAR1PPARG
SCHEMBL8975421 0.86 FFAR1 (0.57) FFAR1PPARGPPARAADRB2ADRB1
SCHEMBL8975446 0.85 PPARG (0.50) FFAR1PPARGPPARA
SCHEMBL8974989 0.85 PPARG (0.56) FFAR1PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5578620-A TREATMENT OF DIABETES AND HYPERLIPEMIA SANKYO COMPANY, LIMITED (JP) 1996-11-26 US disclosed