Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | ATIC | P31939 | 1/20 | 0.42 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28389794 | 0.80 | CDC25B (0.60) | HSD17B10HPGDCYP2C9CDC25BMAPT | |
| SCHEMBL9024276 | 0.79 | ALDH1A1 (0.41) | CYP2C9GAAALOX5ALDH1A1 | |
| SCHEMBL30364459 | 0.75 | STAT3 (0.54) | HSD17B10HPGDMAPTKMT2ACA12 | |
| SCHEMBL7288918 | 0.75 | STAT3 (0.54) | HSD17B10HPGDMAPTKMT2ACA12 | |
| SCHEMBL9627412 | 0.73 | EP300 (0.48) | HSD17B10HPGDTSHRALOX12MAPT | |
| SCHEMBL10582613 | 0.73 | EP300 (0.48) | HSD17B10HPGDTSHRALOX12MAPT | |
| SCHEMBL7718023 | 0.72 | PKM (0.66) | HPGDCYP2C9TSHRMAPTGAA | |
| SCHEMBL9812651 | 0.71 | MAOB (0.51) | HSD17B10HPGDMAPTMAPK1MEN1 | |
| SCHEMBL4044126 | 0.71 | MAPT (0.64) | HSD17B10HPGDCYP2C9TSHRALOX12 | |
| SCHEMBL9054405 | 0.71 | EP300 (0.67) | HSD17B10HPGDTSHRALOX12MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5527948-A | SUBSTITUTED NAPHTHYL-ALKENOIC ACIDS FOR TREATING AUTOIMMUNE DISORDERS | EISAI CORP. LTD. (JP) | 1996-06-18 | — | — | US | disclosed |