Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.63 |
| ▸ | ADH1A | P07327 | 2/20 | 0.96 |
| ▸ | LMNA | P02545 | 1/20 | 0.73 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.73 |
| ▸ | TP53 | P04637 | 1/20 | 0.73 |
| ▸ | TSHR | P16473 | 1/20 | 0.73 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.73 |
| ▸ | P2RY1 | P47900 | 6/20 | 0.70 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.70 |
| ▸ | SRC | P12931 | 1/20 | 0.70 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.70 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.70 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.70 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | LDHA | P00338 | 1/20 | 0.69 |
| ▸ | LDHB | P07195 | 1/20 | 0.69 |
| ▸ | MACROD2 | A1Z1Q3 | 1/20 | 0.66 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrogen Peroxide SCHEMBL9681552 | 0.99 | ADH1A (0.98) | ADH1ALMNAPMP22TP53TSHR | |
| SCHEMBL29740660 | 0.98 | ADH1A (1.00) | ADH1ALMNAPMP22TP53TSHR | |
| SCHEMBL29350404 | 0.98 | ADH1A (1.00) | ADH1ALMNAPMP22TP53TSHR | |
| SCHEMBL29548827 | 0.98 | ADH1A (1.00) | ADH1ALMNAPMP22TP53TSHR | |
| SCHEMBL1276381 | 0.98 | ADH1A (1.00) | ADH1ALMNAPMP22TP53TSHR | |
| SCHEMBL29351291 | 0.98 | ADH1A (1.00) | ADH1ALMNAPMP22TP53TSHR | |
| SCHEMBL8003782 | 0.98 | ADH1A (1.00) | ADH1ALMNAPMP22TP53TSHR | |
| SCHEMBL8187 | 0.98 | ADH1A (1.00) | ADH1ALMNAPMP22TP53TSHR | |
| SCHEMBL20202727 | 0.98 | ADH1A (1.00) | ADH1ALMNAPMP22TP53TSHR | |
| SCHEMBL8188 | 0.98 | ADH1A (1.00) | ADH1ALMNAPMP22TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0704053-A1 | ANALYSIS OF ANALYTES IN BIOLOGICAL FLUIDS | BECKMAN INSTRUMENTS, INC. (US) | 1996-04-03 | — | — | EP | disclosed |
| WO-1995028637-A1 | ANALYSIS OF ANALYTES IN BIOLOGICAL FLUIDS | BECKMAN INSTRUMENTS, INC. (US) | 1995-10-26 | — | — | WO | disclosed |