Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 3/20 | 0.60 |
| ▸ | ADRB2 | P07550 | 11/20 | 0.56 |
| ▸ | ADRB3 | P13945 | 15/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 12/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7148487 | 0.89 | SLC2A1 (0.69) | SLC2A1ADRB2ADRB3ADRB1GLA | |
| SCHEMBL7211873 | 0.89 | SLC2A1 (0.69) | SLC2A1ADRB2ADRB3ADRB1GLA | |
| SCHEMBL8301319 | 0.89 | SLC2A1 (0.69) | SLC2A1ADRB2ADRB3ADRB1GLA | |
| SCHEMBL7148491 | 0.89 | SLC2A1 (0.69) | SLC2A1ADRB2ADRB3ADRB1GLA | |
| Hydrochloric Acid SCHEMBL11544573 | 0.84 | ADRB2 (0.74) | ADRB2ADRB3ADRB1CYP3A4HIF1A | |
| SCHEMBL11168722 | 0.84 | SLC2A1 (0.72) | SLC2A1ADRB2ADRB3ADRB1GLA | |
| SCHEMBL10840645 | 0.83 | SLC2A1 (0.70) | SLC2A1ADRB2ADRB3ADRB1CYP2D6 | |
| SCHEMBL10890383 | 0.83 | SLC2A1 (0.70) | SLC2A1ADRB2ADRB3ADRB1CYP2D6 | |
| SCHEMBL11172822 | 0.83 | SLC2A1 (0.64) | SLC2A1ADRB2ADRB3ADRB1GLA | |
| SCHEMBL10838570 | 0.80 | SLC2A1 (0.67) | SLC2A1ADRB2ADRB3ADRB1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5482971-A | Beta3 -adrenergic agents and their use in pharmaceutical compositions | AMERICAN CYANAMID COMPANY (US) | 1996-01-09 | — | — | US | disclosed |