Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | PPARG | P37231 | 10/20 | 0.51 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9570616 | 0.82 | MAPT (0.61) | MAPTPPARGMAOACISD1ALDH1A1 | |
| SCHEMBL8173771 | 0.81 | MAPT (0.65) | MAPTPPARGMAOACISD1ALDH1A1 | |
| SCHEMBL9516553 | 0.81 | MAPT (0.65) | MAPTPPARGMAOACISD1ALDH1A1 | |
| SCHEMBL9570600 | 0.81 | MAPT (0.69) | MAPTPPARGMAOACISD1ALDH1A1 | |
| SCHEMBL9570606 | 0.81 | MAPT (0.69) | MAPTPPARGMAOACISD1ALDH1A1 | |
| SCHEMBL9570680 | 0.81 | MAPT (0.60) | MAPTPPARGMAOACISD1ALDH1A1 | |
| SCHEMBL9570559 | 0.81 | MAPT (0.83) | MAPTPPARGMAOACISD1ALDH1A1 | |
| SCHEMBL9371970 | 0.79 | MAPT (0.65) | MAPTPPARGMAOACISD1ALDH1A1 | |
| SCHEMBL9375186 | 0.78 | PPARG (0.61) | MAPTPPARGMAOACISD1ALDH1A1 | |
| SCHEMBL9617824 | 0.78 | MAPT (0.53) | MAPTPPARGMAOACISD1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578620-A | TREATMENT OF DIABETES AND HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 1996-11-26 | — | — | US | disclosed |
| EP-0705160-A1 | FUNGICIDAL ACTIVE-SUBSTANCE COMBINATION | BAYER AG (DE) | 1996-04-10 | — | — | EP | disclosed |
| EP-0678511-A2 | Thiazolidine and oxazolidine derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1995-10-25 | — | — | EP | disclosed |
| WO-1995000303-A1 | FUNGICIDAL ACTIVE-SUBSTANCE COMBINATION | BAYER AKTIENGESELLSCHAFT (DE) | 1995-01-05 | — | — | WO | disclosed |