SCHEMBL8975257

SCHEMBL8975257

C=CC1CNCCC1CC(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A11 P48066 6/20 0.50
SLC6A13 Q9NSD5 6/20 0.50
SLC6A12 P48065 5/20 0.50
SLC6A1 P30531 4/20 0.50
GABRA5 P31644 3/20 0.50
GABRB2 P47870 3/20 0.50
GABRA1 P14867 2/20 0.50
GABRA4 P48169 2/20 0.50
GABRR1 P24046 1/20 0.50
TSHR P16473 2/20 0.32
LMNA P02545 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
GABRP O00591 1/20 0.31
GABRD O14764 1/20 0.31
GABRB1 P18505 1/20 0.31
GABRG2 P18507 1/20 0.31
GABRB3 P28472 1/20 0.31
GABRA3 P34903 1/20 0.31
GABRA2 P47869 1/20 0.31
GABRE P78334 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11480598 1.00 SLC6A11 (0.50) SLC6A11SLC6A13SLC6A12SLC6A1GABRA5
SCHEMBL5654853 1.00 SLC6A11 (0.50) SLC6A11SLC6A13SLC6A12SLC6A1GABRA5
SCHEMBL5654855 1.00 SLC6A11 (0.50) SLC6A11SLC6A13SLC6A12SLC6A1GABRA5
Hydrochloric Acid SCHEMBL6217807 0.98 SLC6A11 (0.49) SLC6A11SLC6A13SLC6A12SLC6A1GABRA5
SCHEMBL5765816 0.81 SLC6A1 (0.34) SLC6A11SLC6A13SLC6A12SLC6A1GABRA5
SCHEMBL5765812 0.81 SLC6A1 (0.34) SLC6A11SLC6A13SLC6A12SLC6A1GABRA5
SCHEMBL11481905 0.80 MAPT (0.36) SLC6A11SLC6A13SLC6A12SLC6A1GABRA5
SCHEMBL11481909 0.80 MAPT (0.36) SLC6A11SLC6A13SLC6A12SLC6A1GABRA5
SCHEMBL11481907 0.80 MAPT (0.36) SLC6A11SLC6A13SLC6A12SLC6A1GABRA5
SCHEMBL10354008 0.77 SLC6A1 (0.32) SLC6A11SLC6A13SLC6A12SLC6A1GABRA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5523367-A DISPOSABLE PRODUCTS PHILLIPS PETROLEUM COMPANY (US) 1996-06-04 US disclosed
US-5484865-A Copolymers of ampholytic ion pairs containing vinylic tertiary amine PHILLIPS PETROLEUM COMPANY (US) 1996-01-16 US disclosed
US-5294691-A Absorbing an aqueous soution of the copolymer having amide, nitrile, carboxylic acid or sulfonic acid functionalities PHILLIPS PETROLEUM COMPANY (US) 1994-03-15 US disclosed
US-5250642-A High absorbency to aqueous electrolyte solutions PHILLIPS PETROLEUM COMPANY (US) 1993-10-05 US disclosed
US-4238612-A Process for the isomerization of derivatives of 3-vinyl-piperidine PHARMINDUSTRIE (FR) 1980-12-09 US disclosed