Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3211981 | 0.78 | HTR2A (0.36) | HTR2ATAAR1HRH1DPP4F2 | |
| SCHEMBL1129056 | 0.78 | TAAR1 (0.52) | TAAR1TSHR | |
| SCHEMBL29936912 | 0.78 | TRPA1 (0.41) | HTR2ATAAR1HRH1DPP4F2 | |
| SCHEMBL2486698 | 0.78 | MAPT (0.36) | HTR2ATAAR1MEN1KMT2AALDH1A1 | |
| SCHEMBL16426370 | 0.78 | HTR2A (0.36) | HTR2ATAAR1HRH1DPP4F2 | |
| SCHEMBL610027 | 0.78 | LMNA (0.52) | KMT2AKDM4ELMNATSHRRAB9A | |
| SCHEMBL15195448 | 0.78 | LMNA (0.52) | KMT2AKDM4ELMNATSHRRAB9A | |
| SCHEMBL8535055 | 0.78 | SCN4A (0.45) | HTR2ATAAR1DPP4F2 | |
| SCHEMBL1120259 | 0.78 | SCN4A (0.45) | HTR2ATAAR1DPP4F2 | |
| Hydrochloric Acid SCHEMBL8534949 | 0.77 | SCN4A (0.44) | HTR2ATAAR1DPP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543919-B1 | USE OF HETEROCYCLIC AMINO-ALCOHOL COMPOUNDS IN THE MANUFACTURE OF A MEDICAMENT FOR TREATMENT OF CNS DISEASES | SEARLE & CO (US) | 1996-04-10 | — | — | EP | claimed |