Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | BCL9 | O00512 | 2/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.33 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.32 |
| ▸ | RHEB | Q15382 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | PDE1A | P54750 | 1/20 | 0.31 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.31 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8631618 | 0.99 | TOP2A (0.37) | TOP2AIDO1TDO2PLAUKDM4E | |
| Hydrochloric Acid SCHEMBL7880941 | 0.99 | TOP2A (0.37) | TOP2AIDO1TDO2PLAUKDM4E | |
| Hydrochloric Acid SCHEMBL7881203 | 0.94 | BACE1 (0.34) | TOP2AIDO1TDO2KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL8632298 | 0.94 | BACE1 (0.34) | TOP2AIDO1TDO2KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL7879736 | 0.90 | SLC6A9 (0.34) | IDO1TDO2KDM4EALDH1A1MEN1 | |
| SCHEMBL9413529 | 0.90 | KDM4E (0.43) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8628011 | 0.89 | KDM4E (0.42) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7873554 | 0.89 | KDM4E (0.42) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7873324 | 0.89 | PRKAB2 (0.34) | IDO1TDO2KDM4EALDH1A1MEN1 | |
| SCHEMBL7884730 | 0.89 | PLAU (0.37) | IDO1TDO2PLAUKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8208602-A | — | — | None | — | — | JP | disclosed |
| JP-H08208602-A | INDOLOYLGUANIDINE DERIVATIVE | SUMITOMO PHARMACEUT CO LTD | 1996-08-13 | — | — | JP | disclosed |