Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 2/20 | 0.34 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | BCL9 | O00512 | 2/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8631624 | 0.99 | TOP2A (0.39) | TOP2AIDO1TDO2PLAUSUCNR1 | |
| Hydrochloric Acid SCHEMBL7880944 | 0.99 | TOP2A (0.39) | TOP2AIDO1TDO2PLAUSUCNR1 | |
| Hydrochloric Acid SCHEMBL7881208 | 0.94 | TOP2A (0.34) | TOP2AIDO1TDO2KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL8632300 | 0.94 | TOP2A (0.34) | TOP2AIDO1TDO2KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL7879738 | 0.91 | SCD (0.35) | TOP2AIDO1TDO2KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL7873332 | 0.90 | PRKAB2 (0.34) | IDO1TDO2KDM4EHPGDPKM | |
| SCHEMBL9413530 | 0.89 | KDM4E (0.41) | KDM4ETDP1HTR2AGAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7873675 | 0.89 | SMN1; SMN2 (0.34) | IDO1TDO2KDM4EHPGDPKM | |
| SCHEMBL8631812 | 0.88 | TDP1 (0.45) | IDO1TDO2PLAUKDM4EHPGD | |
| SCHEMBL7884732 | 0.88 | KMT2A (0.38) | KDM4EHPGDPKMTSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8208602-A | — | — | None | — | — | JP | disclosed |
| JP-H08208602-A | INDOLOYLGUANIDINE DERIVATIVE | SUMITOMO PHARMACEUT CO LTD | 1996-08-13 | — | — | JP | disclosed |