Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8628017 | 0.99 | KDM4E (0.40) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7873557 | 0.99 | KDM4E (0.40) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7884769 | 0.94 | KDM4E (0.39) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8633729 | 0.94 | KDM4E (0.39) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8975389 | 0.89 | TOP2A (0.37) | KDM4ESMN1; SMN2GAAHTR2ATDP1 | |
| Hydrochloric Acid SCHEMBL7879941 | 0.88 | KDM4E (0.38) | KDM4EALDH1A1SMN1; SMN2GAAMAPK1 | |
| Hydrochloric Acid SCHEMBL7880944 | 0.88 | TOP2A (0.39) | KDM4ESMN1; SMN2GAAHTR2ATDP1 | |
| Hydrochloric Acid SCHEMBL7879738 | 0.88 | SCD (0.35) | KDM4ESMN1; SMN2GAATDP1 | |
| Hydrochloric Acid SCHEMBL8631624 | 0.88 | TOP2A (0.39) | KDM4ESMN1; SMN2GAAHTR2ATDP1 | |
| Hydrochloric Acid SCHEMBL7873332 | 0.87 | PRKAB2 (0.34) | KDM4EALDH1A1SMN1; SMN2KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0622356-A1 | Indoloylguanidine derivatives as inhibitors of sodium-hydrogen exchange | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1994-11-02 | — | — | EP | disclosed |