Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8975400 | 0.85 | MEN1 (0.38) | MEN1KMT2ACYP1A2HRH1CYP2C19 | |
| SCHEMBL29358101 | 0.76 | MEN1 (0.59) | MEN1KMT2ACYP1A2HRH1CYP2C19 | |
| SCHEMBL3680646 | 0.76 | MEN1 (0.59) | MEN1KMT2ACYP1A2HRH1CYP2C19 | |
| SCHEMBL1345079 | 0.75 | CA2 (0.35) | TP53 | |
| Sulfuric Acid SCHEMBL5787947 | 0.74 | SLC22A16 (0.45) | MEN1KMT2ALMNASMN1; SMN2TP53 | |
| SCHEMBL27615332 | 0.73 | CYP1A2 (0.40) | MEN1KMT2ACYP1A2CYP2C19LMNA | |
| Ammonia Solution, Strong SCHEMBL11133017 | 0.73 | CA2 (0.33) | TP53 | |
| SCHEMBL20553266 | 0.73 | CA2 (0.33) | TP53 | |
| Water SCHEMBL345127 | 0.73 | CA2 (0.33) | TP53 | |
| SCHEMBL17920061 | 0.71 | MAPT (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5575821-A | Process for the preparation of a modified fiber material and process for the dyeing of the modified material with anionic textile dyes | HOECHST AG (DE) | 1996-11-19 | — | — | US | disclosed |
| US-5507840-A | FIBERS MODIFIED WITH COMPOUND CONTAINING HYDROXY, AMINE AND AT LEAST ONE HYDROLYZABLE ESTER GROUPS | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-04-16 | — | — | US | disclosed |