Water

Water

SCHEMBL345127

O.O=S(=O)(O)OC(CO)CO

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.33
TP53 P04637 1/20 0.33
TSHR P16473 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1345079 0.97 CA2 (0.35) CA2TP53TSHRTDP1
SCHEMBL20553266 0.94 CA2 (0.33) CA2TP53TSHRTDP1
Ammonia Solution, Strong SCHEMBL11133017 0.94 CA2 (0.33) CA2TP53TSHRTDP1
Ether SCHEMBL9711364 0.84 ALDH1A1 (0.32)
SCHEMBL17920061 0.82 MAPT (0.31)
SCHEMBL9797147 0.82 TP53 (0.31) TP53TSHRTDP1
SCHEMBL8329444 0.82
SCHEMBL720024 0.80
SCHEMBL720023 0.77
SCHEMBL345128 0.74 USP2 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 417 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12415876-B2 Method for producing vinyl chloride-based polymer LG CHEM, LTD. (KR) 2025-09-16 US claimed
CN-119157769-A Application of rhamnolipid in improving transparency and shampoo 万华化学集团股份有限公司 2024-12-20 CN claimed
EP-4029885-B1 METHOD FOR PRODUCING VINYL CHLORIDE-BASED POLYMER LG CHEMICAL LTD (KR) 2024-12-18 EP claimed
CN-113748139-B Process for preparing chlorovinyl polymer 株式会社LG化学 2023-07-28 CN claimed
US-20220227899-A1 METHOD FOR PRODUCING VINYL CHLORIDE-BASED POLYMER LG CHEM, LTD. (KR) 2022-07-21 US claimed
EP-4029885-A1 METHOD FOR PREPARING VINYL CHLORIDE-BASED POLYMER LG CHEM, LTD. (KR) 2022-07-20 EP claimed
CN-113748139-A Process for producing vinyl chloride-based polymer 株式会社LG化学 2021-12-03 CN claimed
WO-2021049836-A1 METHOD FOR PREPARING VINYL CHLORIDE-BASED POLYMER 주식회사 엘지화학 2021-03-18 WO claimed
CN-110960434-A Scalp care shampoo composition and preparation method thereof 广州市科能化妆品科研有限公司 2020-04-07 CN claimed
CN-107001984-B Detergent compositions comprising branched surfactants 宝洁公司 2019-11-12 CN claimed
CN-1281507-A Detergent-making process using high active surfactant paste containing mid-chain branched surfactants PROCTER & GAMBLE (US) 2001-01-24 CN claimed
CN-1281505-A Process for making high density granular detergent compositions containing mid-chain branched surfactants PROCTER & GAMBLE (US) 2001-01-24 CN claimed
CN-1276823-A Detergent composition PROCTER & GAMBLE (US) 2000-12-13 CN claimed
CN-1276822-A Mid-chain branched surfactants with potassium ions PROCTER & GAMBLE (US) 2000-12-13 CN claimed
CN-1276004-A Mid-chain branched surfactands with cellulose derivatives PROCTER & GAMBLE (US) 2000-12-06 CN claimed
CN-1222187-A Mid-chain branched surfactants PROCTER & GAMBLE (US) 1999-07-07 CN claimed
US-5580850-A CONTAINING QUATERNIZED FATTY ACID ALKANOLAMINE ESTER HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1996-12-03 US claimed
CN-1136078-A Detergent composition KAO CORP (JP) 1996-11-20 CN claimed
US-5158692-A Unsaturated carboxylic ester sulfonate compound and sulfate compound HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1992-10-27 US claimed
US-5117032-A Reaction of sulfur trioxide with glycerol ethers HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1992-05-26 US claimed