Phenylalanine

Phenylalanine

SCHEMBL8975478

CC[C@H](C)[C@H](N)C(=O)O.C[C@H](N)C(=O)O.N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 6/20 0.65
ALPI P09923 1/20 0.65
PKM P14618 1/20 0.65
PTGS1 P23219 1/20 0.65
XIAP P98170 1/20 0.65
SLC1A3 P43003 2/20 0.51
SLC1A2 P43004 2/20 0.51
SLC1A1 P43005 2/20 0.51
ACE P12821 2/20 0.49
CTSC P53634 1/20 0.46
MME P08473 1/20 0.46
CPA1 P15085 1/20 0.46
ACE2 Q9BYF1 1/20 0.46
NOS3 P29474 1/20 0.46
NOS1 P29475 1/20 0.46
NOS2 P35228 1/20 0.46
SLC15A1 P46059 1/20 0.45
TRPA1 O75762 1/20 0.45
LTA4H P09960 1/20 0.45
CYP2D6 P10635 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenylalanine SCHEMBL528154 0.97 SLC7A5 (0.69) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL1537266 0.97 SLC7A5 (0.69) SLC7A5ALPIPKMPTGS1XIAP
D-Phenylalanine SCHEMBL1537463 0.97 SLC7A5 (0.69) SLC7A5ALPIPKMPTGS1XIAP
D-Phenylalanine SCHEMBL1537166 0.97 SLC7A5 (0.69) SLC7A5ALPIPKMPTGS1XIAP
D-Phenylalanine SCHEMBL1537167 0.97 SLC7A5 (0.69) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL528153 0.97 SLC7A5 (0.69) SLC7A5ALPIPKMPTGS1XIAP
D-Phenylalanine SCHEMBL1537464 0.97 SLC7A5 (0.69) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL7524862 0.93 SLC7A5 (0.63) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL7524865 0.93 SLC7A5 (0.63) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL10598020 0.92 SLC7A5 (0.61) SLC7A5ALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0248838-A1 COMPOSITIONS FOR COMBATTING DIARRHOEA VERENIGING VOOR CHRISTELIJK WETENSCHAPPELIJK ONDERWIJS (NL) 1987-12-16 EP claimed
WO-1987003485-A1 COMPOSITIONS FOR COMBATTING DIARRHOEA VERENIGING VOOR CHRISTELIJK WETENSCHAPPELIJK ONDER (NL) 1987-06-18 WO claimed
US-5500208-A Oral compositions comprising a novel tripeptide THE PROCTER & GAMBLE COMPANY (US) 1996-03-19 US disclosed
WO-1995033764-A2 ORAL COMPOSITIONS COMPRISING A NOVEL TRIPEPTIDE PROCTER & GAMBLE (US) 1995-12-14 WO disclosed
EP-0248838-A1 COMPOSITIONS FOR COMBATTING DIARRHOEA VERENIGING VOOR CHRISTELIJK WETENSCHAPPELIJK ONDERWIJS (NL) 1987-12-16 EP disclosed
WO-1987003485-A1 COMPOSITIONS FOR COMBATTING DIARRHOEA VERENIGING VOOR CHRISTELIJK WETENSCHAPPELIJK ONDER (NL) 1987-06-18 WO disclosed