Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 6/20 | 0.69 |
| ▸ | ALPI | P09923 | 1/20 | 0.69 |
| ▸ | PKM | P14618 | 1/20 | 0.69 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.69 |
| ▸ | XIAP | P98170 | 1/20 | 0.69 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.54 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.54 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.54 |
| ▸ | ACE | P12821 | 2/20 | 0.51 |
| ▸ | CTSC | P53634 | 1/20 | 0.48 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | CPA1 | P15085 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.48 |
| ▸ | NOS3 | P29474 | 1/20 | 0.48 |
| ▸ | NOS1 | P29475 | 1/20 | 0.48 |
| ▸ | NOS2 | P35228 | 1/20 | 0.48 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| D-Phenylalanine SCHEMBL1537463 | 1.00 | SLC7A5 (0.69) | SLC7A5ALPIPKMPTGS1XIAP | |
| D-Phenylalanine SCHEMBL1537167 | 1.00 | SLC7A5 (0.69) | SLC7A5ALPIPKMPTGS1XIAP | |
| D-Phenylalanine SCHEMBL1537166 | 1.00 | SLC7A5 (0.69) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanine SCHEMBL1537266 | 1.00 | SLC7A5 (0.69) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanine SCHEMBL528154 | 1.00 | SLC7A5 (0.69) | SLC7A5ALPIPKMPTGS1XIAP | |
| D-Phenylalanine SCHEMBL1537464 | 1.00 | SLC7A5 (0.69) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanine SCHEMBL8975478 | 0.97 | SLC7A5 (0.65) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanine SCHEMBL7524865 | 0.96 | SLC7A5 (0.63) | SLC7A5ALPIPKMPTGS1XIAP | |
| Dl-Phenylalanine SCHEMBL7524862 | 0.96 | SLC7A5 (0.63) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanine SCHEMBL10598020 | 0.94 | SLC7A5 (0.61) | SLC7A5ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10662210-B2 | Compositions and methods comprising osmium for the treatment of cancers | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-05-26 | — | — | US | claimed |
| US-20190276484-A1 | COMPOSITIONS AND METHODS COMPRISING OSMIUM FOR THE TREATMENT OF CANCERS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-09-12 | — | — | US | claimed |
| US-20170233422-A1 | COMPOSITIONS AND METHODS COMPRISING OSMIUM FOR THE TREATMENT OF CANCERS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-08-17 | — | — | US | claimed |
| WO-2016004156-A1 | COMPOSITIONS AND METHODS COMPRISING OSMIUM FOR TREATMENT OF CANCERS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-01-07 | — | — | WO | claimed |
| EP-3487489-B1 | HD ACID CONCENTRATE WITH AMINO ACIDS | FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH (DE) | 2023-12-20 | — | — | EP | disclosed |
| WO-2023230512-A1 | COMPOSITIONS FOR MAINTAINING LENTIVIRAL VECTOR AND USES THEREOF | 2SEVENTY BIO, INC. (US) | 2023-11-30 | — | — | WO | disclosed |
| CN-115901987-A | Protein precipitant, kit and method for detecting heart failure and coronary heart disease markers | 华中科技大学同济医学院附属同济医院 | 2023-04-04 | — | — | CN | disclosed |
| US-20220133667-A1 | Method of Making a Magnesium Salt of an Alpha Keto Acid of Leucine, Isoleucine, and Valine | Hull, Jr., Edgar L. (US) | 2022-05-05 | — | — | US | disclosed |
| US-11318470-B2 | Microfluidics-based nanobiosensors and devices | KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2022-05-03 | — | — | US | disclosed |
| US-11253496-B2 | Alpha keto acid compositions for treating hypo-albuminemia | Hull, Edgar L. (US) | 2022-02-22 | — | — | US | disclosed |
| US-11141395-B2 | HD acid concentrate with amino acids | FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH (DE) | 2021-10-12 | — | — | US | disclosed |
| CN-107936110-B | Function and mechanism of mutant gene Nasp in onset of autoimmune disease of lupus model mouse | 潍坊医学院 | 2021-06-22 | — | — | CN | disclosed |
| EP-0710245-A1 | LINEAR SUBSTITUTED OLIGOALKYLENEIMINE LIBRARIES | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 1996-05-08 | — | — | EP | disclosed |
| EP-0710245-A4 | LINEAR SUBSTITUTED OLIGOALKYLENEIMINE LIBRARIES | TORREY PINES INST (US) | 1996-03-12 | — | — | EP | disclosed |
| WO-1994026775-A1 | LINEAR SUBSTITUTED OLIGOALKYLENEIMINE LIBRARIES | HOUGHTEN PHARMACEUTICALS, INC. (US) | 1994-11-24 | — | — | WO | disclosed |
| EP-0358660-B1 | SYNTHETIC INHIBITORS OF MAMMALIAN COLLAGENASE | RES CORP TECHNOLOGIES INC (US) | 1994-05-25 | — | — | EP | disclosed |
| EP-0420883-B1 | TRICYCLIC 3-OXO-PROPANENITRILE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | ERBA CARLO SPA (IT) | 1993-11-03 | — | — | EP | disclosed |
| EP-0358660-A4 | SYNTHETIC INHIBITORS OF MAMMALIAN COLLAGENASE | — | 1991-01-09 | — | — | EP | disclosed |
| EP-0358660-A1 | SYNTHETIC INHIBITORS OF MAMMALIAN COLLAGENASE. | RES CORP TECHNOLOGIES INC (US) | 1990-03-21 | — | — | EP | disclosed |
| WO-1988006890-A1 | SYNTHETIC INHIBITORS OF MAMMALIAN COLLAGENASE | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1988-09-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10662210-B2 | Compositions and methods comprising osmium for the treatment of cancers | OGFR, OTC, EGFR | SLC7A5 2399/4885ALPI 2155/4885PKM 2373/4885 |
| US-20190276484-A1 | COMPOSITIONS AND METHODS COMPRISING OSMIUM FOR THE TREATMENT OF CANCERS | OGFR, OTC, EGFR | SLC7A5 2399/4885ALPI 2155/4885PKM 2373/4885 |
| US-20170233422-A1 | COMPOSITIONS AND METHODS COMPRISING OSMIUM FOR THE TREATMENT OF CANCERS | OGFR, OTC, EGFR | SLC7A5 2399/4885ALPI 2155/4885PKM 2373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.