Phenylalanine

Phenylalanine

SCHEMBL528154

CC[C@H](C)[C@H](N)C(=O)O.N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 6/20 0.69
ALPI P09923 1/20 0.69
PKM P14618 1/20 0.69
PTGS1 P23219 1/20 0.69
XIAP P98170 1/20 0.69
SLC1A3 P43003 2/20 0.54
SLC1A2 P43004 2/20 0.54
SLC1A1 P43005 2/20 0.54
ACE P12821 2/20 0.51
CTSC P53634 1/20 0.48
MME P08473 1/20 0.48
CPA1 P15085 1/20 0.48
ACE2 Q9BYF1 1/20 0.48
NOS3 P29474 1/20 0.48
NOS1 P29475 1/20 0.48
NOS2 P35228 1/20 0.48
SLC15A1 P46059 1/20 0.47
TRPA1 O75762 1/20 0.47
CYP2D6 P10635 1/20 0.47
LTA4H P09960 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dl-Phenylalanine SCHEMBL528153 1.00 SLC7A5 (0.69) SLC7A5ALPIPKMPTGS1XIAP
D-Phenylalanine SCHEMBL1537463 1.00 SLC7A5 (0.69) SLC7A5ALPIPKMPTGS1XIAP
D-Phenylalanine SCHEMBL1537167 1.00 SLC7A5 (0.69) SLC7A5ALPIPKMPTGS1XIAP
D-Phenylalanine SCHEMBL1537166 1.00 SLC7A5 (0.69) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL1537266 1.00 SLC7A5 (0.69) SLC7A5ALPIPKMPTGS1XIAP
D-Phenylalanine SCHEMBL1537464 1.00 SLC7A5 (0.69) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL8975478 0.97 SLC7A5 (0.65) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL7524865 0.96 SLC7A5 (0.63) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL7524862 0.96 SLC7A5 (0.63) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL10598020 0.94 SLC7A5 (0.61) SLC7A5ALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117069645-A Tryptophan and C2 alkylation modification method for tryptophan-containing polypeptide 兰州大学 2023-11-17 CN claimed
US-10662210-B2 Compositions and methods comprising osmium for the treatment of cancers MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2020-05-26 US claimed
US-20190276484-A1 COMPOSITIONS AND METHODS COMPRISING OSMIUM FOR THE TREATMENT OF CANCERS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2019-09-12 US claimed
US-20170233422-A1 COMPOSITIONS AND METHODS COMPRISING OSMIUM FOR THE TREATMENT OF CANCERS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2017-08-17 US claimed
WO-2016004156-A1 COMPOSITIONS AND METHODS COMPRISING OSMIUM FOR TREATMENT OF CANCERS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2016-01-07 WO claimed
EP-0248838-A1 COMPOSITIONS FOR COMBATTING DIARRHOEA VERENIGING VOOR CHRISTELIJK WETENSCHAPPELIJK ONDERWIJS (NL) 1987-12-16 EP claimed
WO-1987003485-A1 COMPOSITIONS FOR COMBATTING DIARRHOEA VERENIGING VOOR CHRISTELIJK WETENSCHAPPELIJK ONDER (NL) 1987-06-18 WO claimed
CN-117706083-A Chemiluminescent immunoassay kit, preparation method and detection method thereof 深圳市卓润生物科技有限公司 2024-03-15 CN disclosed
US-20240042042-A1 CERAMIDE-LIKE LIPID-BASED DELIVERY VEHICLES AND USES THEREOF CHILDREN'S MEDICAL CENTER CORPORATION (US) 2024-02-08 US disclosed
EP-3487489-B1 HD ACID CONCENTRATE WITH AMINO ACIDS FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH (DE) 2023-12-20 EP disclosed
WO-2023230512-A1 COMPOSITIONS FOR MAINTAINING LENTIVIRAL VECTOR AND USES THEREOF 2SEVENTY BIO, INC. (US) 2023-11-30 WO disclosed
US-11771771-B2 Ceramide-like lipid-based delivery vehicles and uses thereof CHILDREN'S MEDICAL CENTER CORPORATION (US) 2023-10-03 US disclosed
CN-115901987-A Protein precipitant, kit and method for detecting heart failure and coronary heart disease markers 华中科技大学同济医学院附属同济医院 2023-04-04 CN disclosed
EP-0358660-B1 SYNTHETIC INHIBITORS OF MAMMALIAN COLLAGENASE RES CORP TECHNOLOGIES INC (US) 1994-05-25 EP disclosed
EP-0420883-B1 TRICYCLIC 3-OXO-PROPANENITRILE DERIVATIVES AND PROCESS FOR THEIR PREPARATION ERBA CARLO SPA (IT) 1993-11-03 EP disclosed
EP-0358660-A4 SYNTHETIC INHIBITORS OF MAMMALIAN COLLAGENASE 1991-01-09 EP disclosed
EP-0358660-A1 SYNTHETIC INHIBITORS OF MAMMALIAN COLLAGENASE. RES CORP TECHNOLOGIES INC (US) 1990-03-21 EP disclosed
WO-1988006890-A1 SYNTHETIC INHIBITORS OF MAMMALIAN COLLAGENASE RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1988-09-22 WO disclosed
EP-0259891-A2 [Leu 13] motilin, DNAs coding for same and methods for producing same KYOWA HAKKO KOGYO CO., LTD. (JP) 1988-03-16 EP disclosed
EP-0035799-A2 Process for obtaining phenyl alanine SOCIETE DES PRODUITS NESTLE S.A. (CH) 1981-09-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10662210-B2 Compositions and methods comprising osmium for the treatment of cancers OGFR, OTC, EGFR SLC7A5 2399/4885ALPI 2155/4885PKM 2373/4885
US-20190276484-A1 COMPOSITIONS AND METHODS COMPRISING OSMIUM FOR THE TREATMENT OF CANCERS OGFR, OTC, EGFR SLC7A5 2399/4885ALPI 2155/4885PKM 2373/4885
US-20170233422-A1 COMPOSITIONS AND METHODS COMPRISING OSMIUM FOR THE TREATMENT OF CANCERS OGFR, OTC, EGFR SLC7A5 2399/4885ALPI 2155/4885PKM 2373/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.