Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 16/20 | 0.67 |
| ▸ | NPY1R | P25929 | 10/20 | 0.67 |
| ▸ | NPY5R | Q15761 | 9/20 | 0.67 |
| ▸ | NPY2R | P49146 | 6/20 | 0.67 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8975803 | 0.97 | NPY4R (0.68) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL29641056 | 0.97 | NPY4R (0.68) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL29641098 | 0.97 | NPY4R (0.68) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL29981508 | 0.94 | NPY4R (0.75) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL2196176 | 0.94 | NPY4R (0.74) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| SCHEMBL8975469 | 0.94 | NPY4R (0.73) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL29483774 | 0.94 | NPY4R (0.73) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL13563451 | 0.93 | NPY4R (0.72) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| SCHEMBL29461992 | 0.93 | NPY4R (0.63) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL22133073 | 0.93 | NPY4R (0.61) | NPY4RNPY1RNPY5RNPY2RKISS1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0350221-B1 | Dermorphin analogs, their methods of preparation, pharmaceutical compositions, and methods of therapeutic treatment using the same | ASTRA AB (SE) | 1996-04-17 | — | — | EP | disclosed |
| US-5312899-A | Dermorphin analogs | BIOCHEM PHARMA, INC. (CA) | 1994-05-17 | — | — | US | disclosed |
| EP-0350221-A2 | Dermorphin analogs, their methods of preparation, pharmaceutical compositions, and methods of therapeutic treatment using the same | Astra Aktiebolag (SE) | 1990-01-10 | — | — | EP | disclosed |