Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.32 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.32 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.32 |
| ▸ | TST | Q16762 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 5/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7791235 | 0.80 | NLRP3 (0.38) | NLRP3ALDH1A1MAPT | |
| SCHEMBL10071438 | 0.79 | NLRP3 (0.43) | NLRP3ALDH1A1LPAR1MAPT | |
| SCHEMBL6354472 | 0.78 | — | — | |
| SCHEMBL4204792 | 0.78 | — | — | |
| SCHEMBL7868611 | 0.77 | TSHR (0.40) | NLRP3ALDH1A1LPAR1 | |
| SCHEMBL16659676 | 0.75 | HMGCR (0.33) | ALDH1A1MAPT | |
| SCHEMBL7871538 | 0.74 | TSHR (0.37) | ALDH1A1 | |
| SCHEMBL7871528 | 0.72 | CYP2C19 (0.35) | MAPT | |
| SCHEMBL10071457 | 0.72 | NLRP3 (0.43) | NLRP3ALDH1A1LPAR1MAPT | |
| SCHEMBL13484191 | 0.71 | MAOA (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5569675-A | ADMINISTERING TO TREAT BLOOD DISORDERS | BAR ILAN UNIVERSITY (IL) | 1996-10-29 | — | — | US | disclosed |