Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6153637 | 0.84 | RAB9A (0.52) | IDO1RAB9AALDH1A1MAPTHTR2A | |
| SCHEMBL5724177 | 0.80 | IDO1 (0.59) | IDO1RAB9AALDH1A1MAPTHTR2A | |
| SCHEMBL1555636 | 0.80 | ALDH1A1 (0.59) | IDO1RAB9AALDH1A1MAPTHTR2A | |
| Bromide SCHEMBL11274697 | 0.79 | IDO1 (0.57) | IDO1RAB9AALDH1A1MAPTHTR2A | |
| Hydrochloric Acid SCHEMBL1133252 | 0.79 | IDO1 (0.60) | IDO1RAB9AALDH1A1MAPTHTR2A | |
| SCHEMBL7729899 | 0.79 | ALDH1A1 (0.58) | IDO1RAB9AALDH1A1MAPTGAA | |
| SCHEMBL5235557 | 0.79 | IDO1 (0.56) | IDO1RAB9AALDH1A1MAPTHTR2A | |
| SCHEMBL6400055 | 0.78 | IDO1 (0.53) | IDO1RAB9AALDH1A1HTR2AAKR1C3 | |
| SCHEMBL10825542 | 0.78 | RAB9A (0.53) | IDO1RAB9AALDH1A1MAPTHTR2A | |
| SCHEMBL11098324 | 0.78 | HTR2A (0.58) | IDO1RAB9AALDH1A1MAPTHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541317-A | PENICILLIN DERIVATIVES, CYCLIZATION OF ESTERS OR THIOESTERS | SANKYO COMPANY, LIMITED (JP) | 1996-07-30 | — | — | US | disclosed |