Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8046011 | 1.00 | MAPT (0.35) | MAPTLMNAHTTTHRBKMT2A | |
| SCHEMBL9428111 | 0.89 | ELANE (0.36) | THRBKMT2ASMN1; SMN2MEN1GAA | |
| SCHEMBL8039575 | 0.89 | DPP8 (0.37) | MAPTALDH1A1GAA | |
| SCHEMBL10865984 | 0.81 | PLCG1 (0.40) | CYP1A2CYP3A4CYP2C9ALDH1A1SMN1; SMN2 | |
| SCHEMBL10862713 | 0.81 | PLCG1 (0.40) | CYP1A2CYP3A4CYP2C9ALDH1A1SMN1; SMN2 | |
| SCHEMBL10862718 | 0.81 | PLCG1 (0.40) | CYP1A2CYP3A4CYP2C9ALDH1A1SMN1; SMN2 | |
| SCHEMBL8046007 | 0.81 | CACNA1C (0.36) | LMNAKDM4E | |
| SCHEMBL29875254 | 0.80 | PLCG1 (0.39) | CYP1A2CYP3A4CYP2C9ALDH1A1SMN1; SMN2 | |
| SCHEMBL9834843 | 0.79 | ESR1 (0.37) | — | |
| SCHEMBL8038860 | 0.79 | ESR1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541317-A | PENICILLIN DERIVATIVES, CYCLIZATION OF ESTERS OR THIOESTERS | SANKYO COMPANY, LIMITED (JP) | 1996-07-30 | — | — | US | disclosed |