Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 8/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | KDM6B | O15054 | 1/20 | 0.31 |
| ▸ | KDM4A | O75164 | 1/20 | 0.31 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.31 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.31 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.31 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10863704 | 0.89 | ELANE (0.33) | ELANE | |
| SCHEMBL8046011 | 0.89 | MAPT (0.35) | GAATHRBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL8975911 | 0.89 | MAPT (0.35) | GAATHRBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL8046007 | 0.86 | CACNA1C (0.36) | ELANEESR1PTGS1PDE4ACACNA1C | |
| SCHEMBL9834843 | 0.86 | ESR1 (0.37) | ELANEESR1PTGS1PDE4ACACNA1C | |
| SCHEMBL8038860 | 0.86 | ESR1 (0.37) | ELANEESR1PTGS1PDE4ACACNA1C | |
| SCHEMBL9852139 | 0.83 | ELANE (0.32) | ELANE | |
| SCHEMBL9428941 | 0.83 | CACNA1C (0.36) | ESR1PTGS1PDE4ACACNA1C | |
| SCHEMBL9427855 | 0.83 | CACNA1C (0.36) | ESR1PTGS1PDE4ACACNA1C | |
| SCHEMBL21081301 | 0.82 | ESR1 (0.48) | ELANEESR1PTGS1PDE4ACACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5306816-A | Processes for preparing carbapenem derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-26 | — | — | US | disclosed |
| EP-0499196-A1 | Intermediates and process for preparing carbapenem derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-08-19 | — | — | EP | disclosed |