Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.45 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.42 |
| ▸ | IDO1 | P14902 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.38 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.38 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL8866442 | 0.88 | KCNJ6 (0.40) | SLC6A2SLC6A4SLC6A3KCNJ6KCNJ5 | |
| Maleic Acid SCHEMBL8866423 | 0.88 | KCNJ6 (0.40) | SLC6A2SLC6A4SLC6A3KCNJ6KCNJ5 | |
| Clortermine SCHEMBL164137 | 0.80 | PNMT (0.52) | PNMTTAAR1IDO1SLC6A2SLC6A4 | |
| Clortermine SCHEMBL30295323 | 0.80 | PNMT (0.52) | PNMTTAAR1IDO1SLC6A2SLC6A4 | |
| Clortermine SCHEMBL266778 | 0.79 | PNMT (0.50) | PNMTTAAR1IDO1SLC6A2SLC6A4 | |
| Clortermine SCHEMBL30791298 | 0.79 | PNMT (0.50) | PNMTTAAR1IDO1SLC6A2SLC6A4 | |
| SCHEMBL14018901 | 0.77 | IDO1 (0.48) | PNMTTAAR1IDO1SLC6A2SLC6A4 | |
| SCHEMBL14040511 | 0.77 | IDO1 (0.48) | PNMTTAAR1IDO1SLC6A2SLC6A4 | |
| SCHEMBL73408 | 0.76 | IDO1 (0.50) | PNMTTAAR1IDO1SLC6A2SLC6A4 | |
| SCHEMBL155932 | 0.75 | TAAR1 (0.52) | KCNN4TAAR1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5539120-A | Arylalkyl-amines having anticonvulsant and neuroprotective properties | AGENCE SPATIALE EUROPEENNE (FR) | 1996-07-23 | — | — | US | claimed |
| EP-0356035-B1 | Arylkalkyl-amines and -amides having anticonvulsant and neuroprotective properties | ASTRA AB (SE) | 1996-03-13 | — | — | EP | claimed |
| WO-1991011995-A1 | ARYLALKYL-AMINES AND -AMIDES HAVING ANTICONVULSANT AND NEUROPROTECTIVE PROPERTIES | FISONS CORPORATION (US) | 1991-08-22 | — | — | WO | claimed |
| EP-0356035-A2 | Arylkalkyl-amines and -amides having anticonvulsant and neuroprotective properties | Astra Aktiebolag (SE) | 1990-02-28 | — | — | EP | claimed |