SCHEMBL89762

SCHEMBL89762

O=P(O)(OCC=CF)OCC=CF

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
BTN3A1 O00481 2/20 0.38
TSHR P16473 1/20 0.31
FNTA P49354 3/20 0.30
PGGT1B P53609 2/20 0.30
FNTB P49356 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL88240 0.85
SCHEMBL11882140 0.84 LPAR3 (0.32) BTN3A1
Diethanolamine SCHEMBL90546 0.84 BTN3A1 (0.31) BTN3A1
SCHEMBL19326914 0.83
Ammonia Solution, Strong SCHEMBL8940797 0.83 LPAR3 (0.34) BTN3A1FNTAFNTB
SCHEMBL777974 0.81
SCHEMBL4564693 0.81
SCHEMBL4564135 0.81
SCHEMBL89528 0.79 FNTA (0.31) FNTAFNTB
SCHEMBL9491664 0.79 TSHR (0.35) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8049040-B2 Ethylene-tetrafluoroethylene phosphate composition E.I. DU PONT DE NEMOURS AND COMPANY (US) 2011-11-01 US claimed
EP-2293876-A1 ETHYLENE-TETRAFLUOROETHYLENE PHOSPHATE COMPOSITION E. I. du Pont de Nemours and Company (US) 2011-03-16 EP claimed
JP-2010509395-A 2010-03-25 JP claimed
JP-2010509396-A 2010-03-25 JP claimed
US-7674928-B2 polyfluorinated phosphates used as as surfactants and additives for waterproof, oil repellent or antisoilant polymer coatings on substrates such as fibers, wood, paper, leather or stone E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-03-09 US claimed
WO-2009143088-A1 ETHYLENE-TETRAFLUOROETHYLENE PHOSPHATE COMPOSITION E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-11-26 WO claimed
US-20090286885-A1 Ethylene-tetrafluoroethylene phosphate composition E.I. DU PONT DE NEMUOURS AND COMPANY (US) 2009-11-19 US claimed
EP-2086989-A1 POLYFLUOROETHER-BASED PHOSPHATES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-08-12 EP claimed
EP-2084167-A1 FLUOROALKYL PHOSPHATE COMPOSITIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-08-05 EP claimed
US-7541488-B2 Process for the preparation of mono- and bis(fluoroalkyl)phosphoranes and the corresponding acids and phosphates MERCK PATENT GMBH (DE) 2009-06-02 US claimed
US-7470818-B2 has lower levels of fluorine, use as surfactants, additives for coatings providing water repellency, oil repellency and stain resistance; superior surface effects E.I. DU PONT DE NEMOURS & COMPANY (US) 2008-12-30 US claimed
WO-2008060352-A1 FLUOROALKYL PHOSPHATE COMPOSITIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-05-22 WO claimed
WO-2008060353-A1 POLYFLUOROETHER-BASED PHOSPHATES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-05-22 WO claimed
US-20080113085-A1 polyfluorinated phosphates used as as surfactants and additives for waterproof, oil repellent or antisoilant polymer coatings on substrates such as fibers, wood, paper, leather or stone E. I. DU PONT DE NEMOURS AND COMPANY 2008-05-15 US claimed
EP-1685143-B1 METHOD FOR THE PRODUCTION OF MONO(FLUOROALKYL)PHOSPHORANES, BIS(FLUOROALKYL)PHOSPHORANES, AND THE CORRESPONDING ACIDS AND PHOSPHATES MERCK PATENT GMBH (DE) 2007-11-28 EP claimed
US-20070088176-A1 Process for the preparation of mono-and bis(fluoroalkyl)phosphoranes and the corresponding acids and phosphates MERECK PATENT GMBH (DE) 2007-04-19 US claimed
US-8129568-B2 Fluoroalkyl phosphate compositions E.I. DU PONT DE NEMOURS AND COMPANY (US) 2012-03-06 US disclosed
US-8049040-B2 Ethylene-tetrafluoroethylene phosphate composition E.I. DU PONT DE NEMOURS AND COMPANY (US) 2011-11-01 US disclosed
WO-2008060352-A1 FLUOROALKYL PHOSPHATE COMPOSITIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-05-22 WO disclosed
US-20070088176-A1 Process for the preparation of mono-and bis(fluoroalkyl)phosphoranes and the corresponding acids and phosphates MERECK PATENT GMBH (DE) 2007-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070088176-A1 Process for the preparation of mono-and bis(fluoroalkyl)phosphoranes and the corresponding acids and phosphates PPIP5K2, PHOSPHO1, PFKFB1 BTN3A1 2923/4885TSHR 3391/4885FNTA 195/4885
US-20090286885-A1 Ethylene-tetrafluoroethylene phosphate composition TWF2, CLCN2, KCNN2 BTN3A1 2946/4885TSHR 2846/4885FNTA 1563/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.