Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8976314 | 1.00 | USP2 (0.65) | USP2ALOX15TSHRSMN1; SMN2KDM4E | |
| SCHEMBL8976337 | 0.85 | SMN1; SMN2 (0.68) | USP2ALOX15TSHRSMN1; SMN2KDM4E | |
| SCHEMBL8976340 | 0.85 | SMN1; SMN2 (0.68) | USP2ALOX15TSHRSMN1; SMN2KDM4E | |
| SCHEMBL13539640 | 0.84 | TSHR (0.72) | USP2ALOX15TSHRSMN1; SMN2KDM4E | |
| SCHEMBL3574805 | 0.81 | TSHR (0.71) | USP2ALOX15TSHRSMN1; SMN2KDM4E | |
| SCHEMBL3574801 | 0.81 | TSHR (0.71) | USP2ALOX15TSHRSMN1; SMN2KDM4E | |
| SCHEMBL8976297 | 0.78 | MEN1 (0.61) | SMN1; SMN2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8976300 | 0.78 | MEN1 (0.61) | SMN1; SMN2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL27347843 | 0.78 | TSHR (0.67) | USP2ALOX15TSHRSMN1; SMN2KDM4E | |
| SCHEMBL8976338 | 0.77 | SMN1; SMN2 (0.62) | USP2ALOX15TSHRSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0707004-A1 | 1-Arylalcenyl 4-arylmethylpiperazinderivatives, process for their preparation and pharmaceutical composition containing them | ADIR ET COMPAGNIE (FR) | 1996-04-17 | — | — | EP | disclosed |