Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | FAAH | O00519 | 1/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8976365 | 1.00 | MEN1 (0.64) | MEN1KMT2AFAAHSIGMAR1POLB | |
| SCHEMBL8954080 | 0.89 | KMT2A (0.69) | MEN1KMT2AFAAHPKMALDH1A1 | |
| SCHEMBL8954085 | 0.89 | KMT2A (0.69) | MEN1KMT2AFAAHPKMALDH1A1 | |
| SCHEMBL8976665 | 0.88 | SIGMAR1 (0.58) | MEN1KMT2AFAAHSIGMAR1POLB | |
| SCHEMBL8976668 | 0.88 | SIGMAR1 (0.58) | MEN1KMT2AFAAHSIGMAR1POLB | |
| SCHEMBL8976376 | 0.87 | MEN1 (0.67) | MEN1KMT2AFAAHSIGMAR1PKM | |
| SCHEMBL8976630 | 0.87 | MEN1 (0.67) | MEN1KMT2AFAAHSIGMAR1POLB | |
| SCHEMBL8976380 | 0.87 | MEN1 (0.67) | MEN1KMT2AFAAHSIGMAR1PKM | |
| SCHEMBL8976627 | 0.87 | MEN1 (0.67) | MEN1KMT2AFAAHSIGMAR1POLB | |
| SCHEMBL8976614 | 0.81 | SIGMAR1 (0.65) | MEN1KMT2AFAAHSIGMAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1053441-C | Compound with 1-(aryl Chain olefine)-4-(aryl methyl) piperazine structure, preparation process thereof and medicine thereof | ADIR ET CO (FR) | 2000-06-14 | — | — | CN | claimed |
| CN-1133288-A | Compound with 1-(aryl Chain olefine)-4-(aryl methyl) piperazine structure, preparation process thereof and medicine thereof | ADIR (FR) | 1996-10-16 | — | — | CN | claimed |
| EP-0707004-A1 | 1-Arylalcenyl 4-arylmethylpiperazinderivatives, process for their preparation and pharmaceutical composition containing them | ADIR ET COMPAGNIE (FR) | 1996-04-17 | — | — | EP | claimed |
| EP-0707004-A1 | 1-Arylalcenyl 4-arylmethylpiperazinderivatives, process for their preparation and pharmaceutical composition containing them | ADIR ET COMPAGNIE (FR) | 1996-04-17 | — | — | EP | disclosed |