Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | GPR183 | P32249 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HBB | P68871 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8976380 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA12CA2CA9 | |
| SCHEMBL8954085 | 0.92 | KMT2A (0.69) | MEN1KMT2ASMN1; SMN2FAAHLMNA | |
| SCHEMBL8954080 | 0.92 | KMT2A (0.69) | MEN1KMT2ASMN1; SMN2FAAHLMNA | |
| SCHEMBL8976627 | 0.90 | MEN1 (0.67) | MEN1KMT2ASMN1; SMN2FAAHLMNA | |
| SCHEMBL8976630 | 0.90 | MEN1 (0.67) | MEN1KMT2ASMN1; SMN2FAAHLMNA | |
| SCHEMBL8976367 | 0.87 | MEN1 (0.64) | MEN1KMT2ASMN1; SMN2FAAHLMNA | |
| SCHEMBL8976365 | 0.87 | MEN1 (0.64) | MEN1KMT2ASMN1; SMN2FAAHLMNA | |
| SCHEMBL8976297 | 0.80 | MEN1 (0.61) | MEN1KMT2ASMN1; SMN2FAAHLMNA | |
| SCHEMBL8976300 | 0.80 | MEN1 (0.61) | MEN1KMT2ASMN1; SMN2FAAHLMNA | |
| SCHEMBL8976668 | 0.79 | SIGMAR1 (0.58) | MEN1KMT2ASMN1; SMN2FAAHLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0707004-A1 | 1-Arylalcenyl 4-arylmethylpiperazinderivatives, process for their preparation and pharmaceutical composition containing them | ADIR ET COMPAGNIE (FR) | 1996-04-17 | — | — | EP | disclosed |