Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 5/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 5/20 | 0.46 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8976387 | 1.00 | AGTR2 (0.46) | AGTR2AGTR1GP6 | |
| SCHEMBL8976447 | 0.89 | AGTR2 (0.50) | AGTR2AGTR1 | |
| SCHEMBL8976453 | 0.89 | AGTR2 (0.50) | AGTR2AGTR1 | |
| SCHEMBL8131016 | 0.88 | AGTR2 (0.44) | AGTR2AGTR1GP6 | |
| SCHEMBL8976741 | 0.84 | AGTR1 (0.59) | AGTR2AGTR1GP6 | |
| SCHEMBL8119597 | 0.84 | AGTR1 (0.59) | AGTR2AGTR1GP6 | |
| SCHEMBL8976748 | 0.84 | AGTR1 (0.59) | AGTR2AGTR1GP6 | |
| SCHEMBL8636224 | 0.83 | AGTR2 (0.46) | AGTR2AGTR1GP6 | |
| SCHEMBL9422538 | 0.80 | AGTR1 (0.50) | AGTR2AGTR1GP6 | |
| SCHEMBL4447594 | 0.79 | AGTR2 (0.54) | AGTR2AGTR1GP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5508299-A | ANGIOTENSIN CONVERTING ENZYME INHIBITOR, ARTERIAL HYPOTENSIVE AGENT; CARDIOVASCULAR DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-04-16 | — | — | US | claimed |
| US-5508299-A | ANGIOTENSIN CONVERTING ENZYME INHIBITOR, ARTERIAL HYPOTENSIVE AGENT; CARDIOVASCULAR DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-04-16 | — | — | US | disclosed |