Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 4/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.57 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.57 |
| ▸ | ITGAL | P20701 | 1/20 | 0.57 |
| ▸ | CA4 | P22748 | 1/20 | 0.57 |
| ▸ | CA6 | P23280 | 1/20 | 0.57 |
| ▸ | ADK | P55263 | 1/20 | 0.57 |
| ▸ | RHEB | Q15382 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | F3 | P13726 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Indole SCHEMBL27416652 | 0.88 | AHR (0.63) | AHRTSHRTRPA1CA1CA2 | |
| 2,6-Dichlorophenol SCHEMBL28901498 | 0.84 | AHR (0.63) | AHRTRPA1CA1CA2ITGB2 | |
| Indole SCHEMBL3268691 | 0.82 | AHR (0.77) | AHRTRPA1CA1CA2ITGB2 | |
| Naphthalene SCHEMBL27867628 | 0.80 | TSHR (0.81) | TSHRCA2CA4ALDH1A1AR | |
| Indole SCHEMBL7216540 | 0.77 | AHR (0.78) | AHRTRPA1CA1CA2ITGB2 | |
| 1-Naphthol SCHEMBL11758881 | 0.77 | CA1 (0.63) | AHRTRPA1CA1CA2ITGB2 | |
| Indole SCHEMBL6386255 | 0.75 | AHR (0.90) | AHRTRPA1CA1CA2ITGB2 | |
| Indole SCHEMBL698 | 0.75 | — | — | |
| Indole SCHEMBL1160186 | 0.75 | AHR (1.00) | AHRTRPA1CA1CA2ITGB2 | |
| Indole SCHEMBL30463845 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0463171-B1 | Method of determining fructosamines | IATRON LAB (JP) | 1996-04-17 | — | — | EP | disclosed |
| US-5312759-A | Method for measurement of fructosamines using 1,2-quinones | IATRON LABORATORIES, INC. (JP) | 1994-05-17 | — | — | US | disclosed |
| EP-0463171-A1 | Method of determining fructosamines | IATRON LABORATORIES, INC. (JP) | 1992-01-02 | — | — | EP | disclosed |