Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.50 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.50 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8976749 | 1.00 | AGTR1 (0.50) | AGTR1AGTR2ABCC4ABCB11PDE3B | |
| SCHEMBL8976651 | 0.85 | GP6 (0.51) | AGTR1AGTR2 | |
| SCHEMBL8976642 | 0.85 | GP6 (0.51) | AGTR1AGTR2 | |
| SCHEMBL8976638 | 0.85 | GP6 (0.51) | AGTR1AGTR2 | |
| SCHEMBL7839395 | 0.81 | AGTR1 (0.48) | AGTR1AGTR2ABCC4ABCB11PDE3B | |
| SCHEMBL8976799 | 0.81 | AGTR1 (0.59) | AGTR1AGTR2 | |
| SCHEMBL8976795 | 0.81 | AGTR1 (0.59) | AGTR1AGTR2 | |
| SCHEMBL8976798 | 0.81 | AGTR1 (0.59) | AGTR1AGTR2 | |
| SCHEMBL9684692 | 0.78 | AGTR1 (0.48) | AGTR1AGTR2ABCC4ABCB11PDE3B | |
| SCHEMBL8976538 | 0.76 | AGTR1 (0.50) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5508299-A | ANGIOTENSIN CONVERTING ENZYME INHIBITOR, ARTERIAL HYPOTENSIVE AGENT; CARDIOVASCULAR DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-04-16 | — | — | US | disclosed |
| EP-0581003-A1 | Imidazolyl substituted cyclohexane derivatives | BAYER AG (DE) | 1994-02-02 | — | — | EP | disclosed |