Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 15/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CCR6 | P51684 | 1/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.50 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL55213 | 0.96 | ALDH1A1 (0.53) | ALDH1A1HTTMAPTHPGDCCR6 | |
| Hydrochloric Acid SCHEMBL27546173 | 0.94 | ALDH1A1 (0.49) | ALDH1A1HTTMAPTHPGDCCR6 | |
| SCHEMBL8088255 | 0.94 | ALDH1A1 (0.52) | ALDH1A1HTTMAPTHPGDCCR6 | |
| SCHEMBL2415227 | 0.94 | ALDH1A1 (0.52) | ALDH1A1HTTMAPTHPGDCCR6 | |
| SCHEMBL5151314 | 0.94 | ALDH1A1 (0.52) | ALDH1A1HTTMAPTHPGDCCR6 | |
| Ethane SCHEMBL27998510 | 0.92 | ALDH1A1 (0.50) | ALDH1A1HTTMAPTHPGDCCR6 | |
| Methyl Alcohol SCHEMBL9412646 | 0.90 | ALDH1A1 (0.49) | ALDH1A1HTTMAPTHPGDCCR6 | |
| SCHEMBL28838564 | 0.85 | ALDH1A1 (0.50) | ALDH1A1HTTMAPTHPGDCCR6 | |
| 2-Mercaptopyrimidine SCHEMBL8105257 | 0.85 | ALDH1A1 (0.47) | ALDH1A1HTTMAPTHPGDCCR6 | |
| SCHEMBL10419946 | 0.85 | ALDH1A1 (0.45) | ALDH1A1HTTMAPTHPGDCCR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0424923-B1 | A silver halide photographic light-sensitive material having a high sensitivity and capable of forming an image with an excellent quality and gradation | KONISHIROKU PHOTO IND (JP) | 1996-04-24 | — | — | EP | disclosed |