SCHEMBL28838564

SCHEMBL28838564

O=S(=O)(Cl)Cl.Sc1nnnn1-c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 0.50
MAPT P10636 5/20 0.50
HPGD P15428 3/20 0.49
HTT P42858 3/20 0.49
CCR6 P51684 1/20 0.49
CACNA1B Q00975 1/20 0.49
APBA1 Q02410 1/20 0.49
NPSR1 Q6W5P4 4/20 0.46
HSD17B10 Q99714 4/20 0.46
LMNA P02545 3/20 0.46
TP53 P04637 1/20 0.46
TSHR P16473 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
GAA P10253 1/20 0.43
PTGS2 P35354 2/20 0.43
POLB P06746 2/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
PKM P14618 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL55213 0.89 ALDH1A1 (0.53) ALDH1A1MAPTHPGDHTTCCR6
SCHEMBL2415227 0.87 ALDH1A1 (0.52) ALDH1A1MAPTHPGDHTTCCR6
SCHEMBL5151314 0.87 ALDH1A1 (0.52) ALDH1A1MAPTHPGDHTTCCR6
SCHEMBL8088255 0.87 ALDH1A1 (0.52) ALDH1A1MAPTHPGDHTTCCR6
Phosphoric Acid SCHEMBL28004344 0.86 ALDH1A1 (0.45) ALDH1A1MAPTHPGDHTTCCR6
Ethane SCHEMBL27998510 0.85 ALDH1A1 (0.50) ALDH1A1MAPTHPGDHTTCCR6
Bromide SCHEMBL8976833 0.85 ALDH1A1 (0.50) ALDH1A1MAPTHPGDHTTCCR6
Methyl Alcohol SCHEMBL9412646 0.84 ALDH1A1 (0.49) ALDH1A1MAPTHPGDHTTCCR6
Hydrochloric Acid SCHEMBL27546173 0.84 ALDH1A1 (0.49) ALDH1A1MAPTHPGDHTTCCR6
SCHEMBL8740829 0.80 LMNA (0.43) ALDH1A1MAPTHPGDHTTCCR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110305069-B Preparation method of 3- (5-mercapto-1-tetrazolyl) benzenesulfonyl chloride 中国乐凯集团有限公司 2022-09-16 CN disclosed