SCHEMBL8976857

SCHEMBL8976857

NC(CC(=O)O)C(CC(=O)O)(CC(=O)O)C(N)(CC(=O)O)CC(=O)O

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.36
GABRR1 P24046 2/20 0.32
LMNA P02545 1/20 0.32
SLC22A6 Q4U2R8 1/20 0.32
KDM4E B2RXH2 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
ALDH1A1 P00352 1/20 0.30
HMGCR P04035 1/20 0.30
CHRM1 P11229 1/20 0.30
TBXA2R P21731 1/20 0.30
ADRA1A P35348 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6270020 0.80 TDP1 (0.33) TDP1GABRR1LMNASLC22A6ALDH1A1
SCHEMBL5690770 0.78 HMGCR (0.38) TDP1GABRR1LMNASLC22A6ALDH1A1
SCHEMBL5692405 0.76 HMGCR (0.37) TDP1GABRR1LMNASLC22A6KDM4E
Ammonia Solution, Strong SCHEMBL10590157 0.76 TDP1 (0.38) TDP1GABRR1LMNASLC22A6ALDH1A1
SCHEMBL465794 0.76 TDP1 (0.40) TDP1GABRR1LMNASLC22A6KDM4E
SCHEMBL750130 0.73 TDP1 (0.42) TDP1GABRR1LMNASLC22A6KDM4E
SCHEMBL8940138 0.72 TSHR (0.30) TDP1
SCHEMBL8940071 0.72 TDP1 (0.30) TDP1
SCHEMBL396503 0.71 TDP1 (0.40) TDP1GABRR1LMNASLC22A6KDM4E
SCHEMBL7999396 0.71 TDP1 (0.40) TDP1GABRR1LMNASLC22A6KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0424923-B1 A silver halide photographic light-sensitive material having a high sensitivity and capable of forming an image with an excellent quality and gradation KONISHIROKU PHOTO IND (JP) 1996-04-24 EP disclosed
EP-0424923-A1 A silver halide photographic light-sensitive material having a high sensitivity and capable of forming an image with an excellent quality and gradation KONICA CORPORATION (JP) 1991-05-02 EP disclosed