Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.68 |
| ▸ | PDE4A | P27815 | 1/20 | 0.68 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.68 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.68 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 4/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.62 |
| ▸ | DPP4 | P27487 | 1/20 | 0.62 |
| ▸ | PREP | P48147 | 1/20 | 0.62 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.62 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8977014 | 1.00 | LMNA (0.69) | LMNAALDH1A1HPGDABCG2PDE4A | |
| SCHEMBL8965003 | 0.95 | LMNA (0.72) | LMNAALDH1A1HPGDABCG2PDE4A | |
| SCHEMBL8965000 | 0.95 | LMNA (0.72) | LMNAALDH1A1HPGDABCG2PDE4A | |
| SCHEMBL8848307 | 0.87 | DBH (0.78) | LMNAALDH1A1HPGDABCG2PDE4A | |
| SCHEMBL8848314 | 0.87 | DBH (0.78) | LMNAALDH1A1HPGDABCG2PDE4A | |
| SCHEMBL25235120 | 0.86 | MAPT (0.72) | LMNAALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL25200295 | 0.86 | MAPT (0.72) | LMNAALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL28263082 | 0.84 | PDE4A (0.90) | LMNAABCG2PDE4APDE4BPDE4C | |
| SCHEMBL15807747 | 0.83 | KRAS (0.77) | LMNAALDH1A1ABCG2MEN1KMT2A | |
| SCHEMBL2458577 | 0.82 | ABCG2 (1.00) | LMNAABCG2PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0428398-B1 | Radiation-sensitive resin composition | JAPAN SYNTHETIC RUBBER CO LTD (JP) | 1996-04-03 | — | — | EP | claimed |
| EP-0428398-A2 | Radiation-sensitive resin composition | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1991-05-22 | — | — | EP | claimed |
| US-5110706-A | Photoresists for highly reflective substrates | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1992-05-05 | — | — | US | disclosed |
| EP-0428398-A2 | Radiation-sensitive resin composition | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1991-05-22 | — | — | EP | disclosed |