Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 3/20 | 0.39 |
| ▸ | GSK3B | P49841 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | CTSG | P08311 | 1/20 | 0.33 |
| ▸ | CMA1 | P23946 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20109312 | 0.76 | GAA (0.33) | GSK3AGSK3BGAASIGMAR1MEN1 | |
| SCHEMBL17596435 | 0.70 | SIGMAR1 (0.39) | SIGMAR1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL19367683 | 0.66 | SMN1; SMN2 (0.36) | GSK3AGSK3BGAAMEN1KMT2A | |
| SCHEMBL10892021 | 0.65 | GSK3A (0.44) | GSK3AGSK3BGAASIGMAR1MEN1 | |
| SCHEMBL9360920 | 0.63 | — | — | |
| SCHEMBL9668729 | 0.59 | SIGMAR1 (0.64) | GAASIGMAR1MEN1NPC1RAB9A | |
| SCHEMBL8966156 | 0.59 | LMNA (0.37) | GSK3AGSK3BGAASIGMAR1MEN1 | |
| SCHEMBL2466051 | 0.58 | LMNA (0.42) | GSK3AGSK3BGAASIGMAR1MEN1 | |
| SCHEMBL6441333 | 0.58 | NOTUM (0.40) | GSK3AGSK3BGAASIGMAR1MEN1 | |
| SCHEMBL576814 | 0.56 | LMNA (0.67) | GAASIGMAR1MEN1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5534646-A | OXIDATION RESISTANCE FOR POLYMERS | CIBA-GEIGY CORPORATION (US) | 1996-07-09 | — | — | US | disclosed |