SCHEMBL8977283

SCHEMBL8977283

Fc1ccc(CCC2CC[SiH](Cl)CC2)cc1

nearest known ligand 0.50

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.50
TAAR1 Q96RJ0 1/20 0.38
KCNH2 Q12809 1/20 0.36
DRD4 P21917 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8083843 0.95 MAOB (0.47) MAOBTAAR1
SCHEMBL7771491 0.95 MAOB (0.47) MAOBTAAR1
SCHEMBL8083840 0.95 MAOB (0.47) MAOBTAAR1
SCHEMBL8434376 0.91 MAOB (0.46) MAOBTAAR1KCNH2DRD4
SCHEMBL8434369 0.91 MAOB (0.46) MAOBTAAR1KCNH2DRD4
SCHEMBL8434372 0.91 MAOB (0.46) MAOBTAAR1KCNH2DRD4
SCHEMBL3716138 0.83 MAOB (0.60) MAOBTAAR1
SCHEMBL8042959 0.82 SLC6A2 (0.38) MAOB
SCHEMBL18715291 0.80 MAOB (0.57) MAOBTAAR1
SCHEMBL23396257 0.78 MAOB (0.55) MAOBTAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5523439-A Process for preparing silacyclohexane compounds SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-06-04 US disclosed
EP-0696592-A1 Process for preparing silacyclohexane compounds SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-02-14 EP disclosed