Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8083843 | 1.00 | MAOB (0.47) | MAOBGPR84MCHR1TAAR1CHRM4 | |
| SCHEMBL7771491 | 1.00 | MAOB (0.47) | MAOBGPR84MCHR1TAAR1CHRM4 | |
| SCHEMBL8977283 | 0.95 | MAOB (0.50) | MAOBTAAR1 | |
| SCHEMBL8434369 | 0.86 | MAOB (0.46) | MAOBTAAR1 | |
| SCHEMBL8434376 | 0.86 | MAOB (0.46) | MAOBTAAR1 | |
| SCHEMBL8434372 | 0.86 | MAOB (0.46) | MAOBTAAR1 | |
| SCHEMBL8015111 | 0.81 | MAOB (0.44) | MAOB | |
| SCHEMBL8092154 | 0.80 | MAOB (0.43) | MAOBGPR84TAAR1 | |
| SCHEMBL8092153 | 0.80 | MAOB (0.43) | MAOBGPR84TAAR1 | |
| SCHEMBL3716138 | 0.79 | MAOB (0.60) | MAOBTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668286-B1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 2000-12-20 | — | — | EP | disclosed |
| US-5523440-A | Silacyclohexane compound, a method of preparaing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0668286-A1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-08-23 | — | — | EP | disclosed |