Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 2/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27719076 | 0.86 | IDH1 (0.58) | IDH1CALM1DAOBCL2BCL2L1 | |
| SCHEMBL8977412 | 0.85 | IDH1 (0.54) | IDH1TSHRCALM1DAOBCL2 | |
| SCHEMBL11389129 | 0.81 | NPC1 (0.46) | IDH1DAOHPGDALOX15KMT2A | |
| SCHEMBL9703621 | 0.81 | IDH1 (0.39) | IDH1DAOMEN1KMT2A | |
| SCHEMBL11195540 | 0.81 | IDH1 (0.53) | IDH1TSHRCALM1DAOBCL2 | |
| SCHEMBL11483794 | 0.81 | IDH1 (0.57) | IDH1CALM1DAOBCL2BCL2L1 | |
| SCHEMBL11173312 | 0.81 | IDH1 (0.53) | IDH1CALM1DAOBCL2BCL2L1 | |
| SCHEMBL15978541 | 0.81 | IDH1 (0.53) | IDH1CALM1DAOBCL2BCL2L1 | |
| SCHEMBL11040268 | 0.78 | IDH1 (0.64) | IDH1CALM1DAOBCL2BCL2L1 | |
| SCHEMBL21153740 | 0.78 | IDH1 (0.50) | IDH1CALM1DAOBCL2BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 361 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1792889-B1 | Process for the preparation of carboxylic acid esters | SUMITOMO CHEMICAL CO (JP) | 2015-03-04 | — | — | EP | claimed |
| US-7741511-B2 | Process for the preparation of carboxylic acid esters | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-06-22 | — | — | US | claimed |
| EP-1404661-B1 | PROCESS FOR THE PRODUCTION OF 5-BENZYL-3-FURFURYL ALCOHOL | ENDURA SPA (IT) | 2008-04-09 | — | — | EP | claimed |
| US-20080009648-A1 | PROCESS FOR THE PREPARATION OF CARBOXYLIC ACID ESTERS | SOUDA HIROSHI | 2008-01-10 | — | — | US | claimed |
| EP-1792889-A2 | Process for the preparation of carboxylic acid esters | Sumitomo Chemical Company, Limited (JP) | 2007-06-06 | — | — | EP | claimed |
| CN-1247560-C | Process for the production of 5-benzyl-3-furfuryl alcohol | ENDURA SPA (IT) | 2006-03-29 | — | — | CN | claimed |
| US-7019154-B2 | Process for the production of 5-benzyl-3-furfuryl alcohol | ENDURA S.P.A. (IT) | 2006-03-28 | — | — | US | claimed |
| EP-1547995-A1 | Process for the preparation of carboxylic acid esters | Sumitomo Chemical Company, Limited (JP) | 2005-06-29 | — | — | EP | claimed |
| US-20050113581-A1 | Process for the preparation of carboxylic acid esters | SUMITOMO CHEMICAL COMPANY, LIMITED | 2005-05-26 | — | — | US | claimed |
| US-20040127728-A1 | Process for the production of 5-benzyl-3-furfuryl alcohol | ENDURA S.P.A. (IT) | 2004-07-01 | — | — | US | claimed |
| EP-0077721-B1 | CYCLOPROPANECARBOXYLIC-ACID DERIVATIVES BEARING AN ALKYLTHIOCARBONYL GROUP, THEIR PREPARATION, THEIR USE AS PARASITICIDES FOR PLANTS, ANIMALS, AND LOCI, AND COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1985-07-03 | — | — | EP | claimed |
| EP-0048186-B1 | CYCLOPROPANE-CARBOXYLIC-ACID DERIVATIVES, THEIR PREPARATION, THEIR USE IN COMBATING VEGETAL PARASITES, ANIMALS AND LOCATIONS, THEIR COMPOSITIONS, AND INTERMEDIATES | ROUSSEL-UCLAF (FR) | 1985-05-02 | — | — | EP | claimed |
| EP-0050534-B1 | ESTERS OF CYCLOPROPANE-CARBOXYLIC ACIDS RELATED TO PYRETHRIC ACID, THEIR PREPARATION AND USE AS INSECTICIDES | ROUSSEL-UCLAF (FR) | 1985-04-03 | — | — | EP | claimed |
| US-4489093-A | Insecticidal esters | ROUSSEL UCLAF (FR) | 1984-12-18 | — | — | US | claimed |
| US-4478850-A | DESTICIDES, NEMATOCIDES, MITICIDES, AND INSECTICIDES | ROUSSEL UCLAF (FR) | 1984-10-23 | — | — | US | claimed |
| EP-0041021-B1 | CYCLOPROPANE CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION, THEIR USE AGAINST PARASITES IN PLANTS AND ANIMALS, THEIR COMPOSITIONS AND THEIR INTERMEDIATES | ROUSSEL-UCLAF (FR) | 1984-07-25 | — | — | EP | claimed |
| EP-0038271-B1 | CYCLOPROPANE CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND USE IN COMBATING PARASITES OF PLANTS AND ANIMALS, THEIR COMPOSITIONS AND INTERMEDIATES | ROUSSEL-UCLAF (FR) | 1984-07-04 | — | — | EP | claimed |
| US-4423243-A | Process for the preparation of 2,2-dimethyl-3-vinyl-cyclopropanecarboxylic acids and esters | BAYER AKTIENGESELLSCHAFT (DE) | 1983-12-27 | — | — | US | claimed |
| US-4332962-A | RHODIUM COMPOUND AS CATALYST FOR CYCLIZATION OF A PENTADIENE | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1982-06-01 | — | — | US | claimed |
| EP-0018894-B1 | ESTERS OF ALLETHROLONE DERIVATIVES AND CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION AND THE COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1982-02-17 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113581-A1 | Process for the preparation of carboxylic acid esters | ACSL6, ALKBH3, ACSL1 | IDH1 1174/4885TSHR 1811/4885CALM1 4097/4885 |
| US-20080009648-A1 | PROCESS FOR THE PREPARATION OF CARBOXYLIC ACID ESTERS | ACSL6, ALKBH3, ACSL1 | IDH1 1174/4885TSHR 1811/4885CALM1 4097/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.