Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | EYA2 | O00167 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27525063 | 0.77 | KDM4E (0.37) | TGFBR1KDM4EALDH1A1TDP1 | |
| SCHEMBL177769 | 0.77 | TDP1 (0.38) | KDM4ETDP1EYA2APPACE | |
| SCHEMBL28825757 | 0.74 | CA12 (0.37) | TGFBR1ALDH1A1TSHR | |
| SCHEMBL11649935 | 0.74 | TGFBR1 (0.38) | TGFBR1ALDH1A1 | |
| SCHEMBL9116946 | 0.72 | CA12 (0.42) | TGFBR1ALDH1A1TSHR | |
| SCHEMBL5461842 | 0.72 | ALDH1A1 (0.33) | TGFBR1ALDH1A1 | |
| SCHEMBL28049819 | 0.71 | TGFBR1 (0.32) | TGFBR1KDM4E | |
| SCHEMBL471930 | 0.69 | — | — | |
| SCHEMBL16268024 | 0.68 | KDM4E (0.45) | TGFBR1KDM4EALDH1A1TDP1EYA2 | |
| SCHEMBL18191955 | 0.68 | TGFBR1 (0.37) | TGFBR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0706520-A1 | NOVEL CROSS-LINKING AGENTS AND USE THEREOF | CULTOR OY (FI) | 1996-04-17 | — | — | EP | disclosed |
| WO-1995001347-A1 | NOVEL CROSS-LINKING AGENTS AND USE THEREOF | CULTOR OY (FI) | 1995-01-12 | — | — | WO | disclosed |