Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.56 |
| ▸ | RAB9A | P51151 | 7/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | SCD | O00767 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4686905 | 0.86 | NPC1 (0.51) | NPC1RAB9AGAASMN1; SMN2PKM | |
| SCHEMBL2543034 | 0.83 | NPC1 (0.54) | NPC1RAB9AGAASMN1; SMN2PKM | |
| SCHEMBL1985103 | 0.80 | NPC1 (0.52) | NPC1RAB9AGAASMN1; SMN2PKM | |
| SCHEMBL10565118 | 0.80 | ELANE (0.71) | NPC1RAB9AGAASMN1; SMN2PKM | |
| SCHEMBL4558136 | 0.78 | SCD (0.66) | NPC1RAB9AGAASMN1; SMN2PKM | |
| SCHEMBL2541602 | 0.78 | PCSK9 (0.52) | NPC1RAB9AGAASMN1; SMN2PKM | |
| SCHEMBL2676462 | 0.77 | ELANE (0.65) | NPC1RAB9AGAASMN1; SMN2PKM | |
| SCHEMBL1990188 | 0.77 | KDM4E (0.53) | NPC1RAB9AGAASMN1; SMN2PKM | |
| SCHEMBL23566353 | 0.76 | SCD (0.63) | NPC1RAB9AGAASMN1; SMN2PKM | |
| SCHEMBL11451768 | 0.76 | ELANE (0.61) | NPC1RAB9AGAASMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0195947-B1 | Beta-lactam antibiotics, process for their preparation and their use as and in medicaments | BAYER AG (DE) | 1996-04-24 | — | — | EP | disclosed |
| CN-1017335-B | PROCESS FOR PREPARING BETA-LACTAM ANTIBIOTICS | BAYER AG (DE) | 1992-07-08 | — | — | CN | disclosed |
| US-RE33948-E | Bactericides, animal growth regulators | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-02 | — | — | US | disclosed |
| US-4748163-A | Novel β-lactam antibiotics | BAYER AKTIENGESELLSCHAFT (DE) | 1988-05-31 | — | — | US | disclosed |
| EP-0195947-A2 | Beta-lactam antibiotics, process for their preparation and their use as and in medicaments | BAYER AG (DE) | 1986-10-01 | — | — | EP | disclosed |