Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | TNF | P01375 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17165001 | 0.87 | KMT2A (0.58) | HTTTDP1PKMALDH1A1SMN1; SMN2 | |
| SCHEMBL468371 | 0.85 | ALDH1A1 (0.51) | TDP1PKMALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL29208563 | 0.82 | GPR35 (0.47) | HTTTDP1ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL8977448 | 0.82 | HTT (0.58) | HTTTDP1PKMSMN1; SMN2KMT2A | |
| SCHEMBL13041709 | 0.81 | HTT (0.57) | HTTTDP1PKMALDH1A1SMN1; SMN2 | |
| Methyl Carbamate SCHEMBL27927217 | 0.80 | HTT (0.65) | HTTTDP1PKMALDH1A1SMN1; SMN2 | |
| Methyl Alcohol SCHEMBL27770206 | 0.80 | HTT (0.68) | HTTTDP1PKMALDH1A1SMN1; SMN2 | |
| SCHEMBL29441283 | 0.79 | HTT (0.72) | HTTTDP1PKMALDH1A1SMN1; SMN2 | |
| SCHEMBL527567 | 0.79 | HTT (0.72) | HTTTDP1PKMALDH1A1SMN1; SMN2 | |
| SCHEMBL5062448 | 0.78 | HTT (0.54) | HTTTDP1PKMALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587509-A | Caged caboxyl compounds and use thereof | CORNELL RESEARCH FOUNDATION, INC. (US) | 1996-12-24 | — | — | US | disclosed |
| US-5430175-A | Caged carboxyl compounds and use thereof | CORNELL RESEARCH FOUNDATION, INC. (US) | 1995-07-04 | — | — | US | disclosed |
| WO-1995015305-A1 | CAGED CARVOXYL COMPOUNDS AND THEIR USE IN CHEMICAL KINETIC INVESTIGATION OF NEUROTRANSMITTER RECEPTORS | CORNELL RESEARCH FOUNDATION, INC. (US) | 1995-06-08 | — | — | WO | disclosed |