Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 3/20 | 0.39 |
| ▸ | FAP | Q12884 | 2/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | KIF11 | P52732 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7164479 | 0.89 | SLC7A5 (0.41) | SLC7A5ACACBDPP4DPP8DPP9 | |
| SCHEMBL17978114 | 0.88 | SLC7A5 (0.45) | SLC7A5ACACBDPP4FAPDPP8 | |
| SCHEMBL17978113 | 0.88 | SLC7A5 (0.45) | SLC7A5ACACBDPP4FAPDPP8 | |
| SCHEMBL10952481 | 0.87 | ACACB (0.44) | SLC7A5ACACBDPP4FAPDPP8 | |
| SCHEMBL11387995 | 0.87 | SLC7A5 (0.51) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL7317870 | 0.86 | SLC6A4 (0.50) | SLC7A5ACACBDPP4FAPDPP8 | |
| SCHEMBL8143842 | 0.86 | SLC6A4 (0.50) | SLC7A5ACACBDPP4FAPDPP8 | |
| SCHEMBL29111947 | 0.86 | ELANE (0.50) | SLC7A5ACACBPPARGPPARAPTPN1 | |
| SCHEMBL11067134 | 0.86 | ACACB (0.49) | SLC7A5ACACBPPARGPPARAPTPN1 | |
| SCHEMBL16415824 | 0.85 | CTSK (0.47) | SLC7A5ACACBDPP4PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486596-A | CYCLIC PEPTIDES | CESKOSLOVENSKA AKADEMIE VED (CS) | 1996-01-23 | — | — | US | disclosed |
| EP-0412508-B1 | Analogues of vasopressin, their preparation and pharmaceutical use | CESKOSLOVENSKA AKADEMIE VED (CS) | 1995-07-05 | — | — | EP | disclosed |
| EP-0412508-A1 | Analogues of vasopressin, their preparation and pharmaceutical use | CESKOSLOVENSKA AKADEMIE VED (CS) | 1991-02-13 | — | — | EP | disclosed |