Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | LDHA | P00338 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 2/20 | 0.43 |
| ▸ | FAP | Q12884 | 2/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | TPH1 | P17752 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8143842 | 1.00 | SLC6A4 (0.50) | SLC6A4LDHACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL11067134 | 0.89 | ACACB (0.49) | SLC6A4LDHAACACBPTPN1SLC7A5 | |
| SCHEMBL29111947 | 0.89 | ELANE (0.50) | SLC6A4LDHAACACBPTPN1SLC7A5 | |
| SCHEMBL7518497 | 0.89 | LDHA (0.53) | SLC6A4LDHACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL7346010 | 0.89 | LDHA (0.53) | SLC6A4LDHACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL106531 | 0.89 | LDHA (0.53) | SLC6A4LDHACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL7164479 | 0.86 | SLC7A5 (0.41) | CYP1A2CYP2D6CYP2C19DPP4DPP8 | |
| SCHEMBL8977513 | 0.86 | SLC7A5 (0.41) | CYP1A2CYP2D6CYP2C19DPP4FAP | |
| SCHEMBL3925157 | 0.86 | ACACB (0.46) | ACACBTPH1PTPN1SLC7A5 | |
| SCHEMBL10952481 | 0.85 | ACACB (0.44) | DPP4FAPDPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4508645-A | CYCLIC OLIGOPEPTIDE CONTAINING PENICILLAMINE RESIDE | CESKOSLOVENSKA AKADEMIE VED (CS) | 1985-04-02 | — | — | US | disclosed |