Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | OGG1 | O15527 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL224515 | 0.84 | KDM4E (0.30) | GAAKDM4E | |
| SCHEMBL2104237 | 0.83 | KDM4E (0.31) | GAAKDM4ETSHR | |
| SCHEMBL13053102 | 0.79 | SORD (0.33) | — | |
| SCHEMBL7258032 | 0.74 | CA12 (0.32) | — | |
| SCHEMBL22075884 | 0.74 | TSHR (0.35) | TSHRSMN1; SMN2MAPTKMT2AALDH1A1 | |
| SCHEMBL9436798 | 0.74 | — | — | |
| SCHEMBL226223 | 0.73 | KDM4E (0.36) | GAAKDM4ETSHRHTTSMN1; SMN2 | |
| SCHEMBL2103475 | 0.72 | TSHR (0.33) | TSHR | |
| SCHEMBL4610394 | 0.72 | HPSE (0.35) | TSHRKMT2AALDH1A1 | |
| SCHEMBL12178890 | 0.69 | KDM4E (0.37) | GAAKDM4ETSHRHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543526-A | 1-amino-4-(1H-imidazole)- aminobutaneboronic acid derivatives, their preparation and use as synthetic intermediates | SYNTHELABO (FR) | 1996-08-06 | — | — | US | disclosed |
| EP-0677525-A1 | Aminoboronic acid derivatives, their preparation as intermediates in syntheses | SYNTHELABO (FR) | 1995-10-18 | — | — | EP | disclosed |