Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.60 |
| ▸ | CES2 | O00748 | 2/20 | 0.57 |
| ▸ | MAOB | P27338 | 3/20 | 0.57 |
| ▸ | CNR2 | P34972 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6425920 | 0.83 | MAOB (0.59) | SRD5A2CES2MAOBCNR2ADORA1 | |
| SCHEMBL1237189 | 0.81 | SRD5A2 (0.79) | SRD5A2CES2MAOBCNR2ALDH1A1 | |
| SCHEMBL1044812 | 0.80 | SRD5A2 (0.83) | SRD5A2CES2MAOBCNR2CNR1 | |
| SCHEMBL2941622 | 0.78 | SRD5A2 (0.81) | SRD5A2CES2CNR2ALDH1A1CNR1 | |
| SCHEMBL8871969 | 0.78 | CYP2D6 (0.50) | MAOB | |
| SCHEMBL9772454 | 0.76 | ATM (0.55) | MAOBMEN1CYP1A2MAPTKMT2A | |
| SCHEMBL9772920 | 0.76 | CYP2D6 (0.54) | MAOBALDH1A1POLBMEN1CYP1A2 | |
| SCHEMBL10514905 | 0.76 | PBRM1 (0.62) | ALDH1A1POLBMEN1CYP1A2MAPT | |
| SCHEMBL9650611 | 0.76 | PARP1 (0.50) | CNR2POLBCNR1MEN1MAPT | |
| SCHEMBL3171076 | 0.76 | KMO (0.55) | ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512537-A | 2-benzoyl pyrrole and benzoyl imidazole herbicides | ZENECA LIMITED (GB) | 1996-04-30 | — | — | US | disclosed |