Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | KAT6A | Q92794 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 2/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL690501 | 0.83 | KAT6A (0.54) | KAT6ATAS1R3TAS1R1TAS1R2NAMPT | |
| SCHEMBL22954042 | 0.82 | KAT6A (0.57) | KAT6ATAS1R3TAS1R1TAS1R2GPR139 | |
| SCHEMBL30668192 | 0.82 | KAT6A (0.57) | KAT6ATAS1R3TAS1R1TAS1R2GPR139 | |
| SCHEMBL11871480 | 0.81 | CES2 (0.57) | CYP2D6RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8977549 | 0.78 | SRD5A2 (0.60) | MAOB | |
| SCHEMBL8871614 | 0.77 | KAT6A (0.44) | KAT6ATAS1R3TAS1R1TAS1R2BRAF | |
| SCHEMBL27361680 | 0.75 | CES2 (0.54) | CYP2D6RAB9ANPC1MAOBSMN1; SMN2 | |
| SCHEMBL9772596 | 0.75 | KMT2A (0.61) | KAT6ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL29459930 | 0.75 | MRGPRX4 (0.61) | KAT6ARAB9ANPC1TAS1R3TAS1R1 | |
| SCHEMBL10561497 | 0.75 | KAT6A (0.52) | KAT6ATAS1R3TAS1R1TAS1R2NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5681795-A | 3-benzoyl pyrrole and pyrazole herbicides | ZENECA LIMITED (GB) | 1997-10-28 | — | — | US | disclosed |