Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 14/20 | 0.81 |
| ▸ | CCKAR | P32238 | 10/20 | 0.81 |
| ▸ | GABRP | O00591 | 1/20 | 0.81 |
| ▸ | GABRD | O14764 | 1/20 | 0.81 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.81 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.81 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.81 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.81 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.81 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.81 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.81 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.81 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.81 |
| ▸ | GABRE | P78334 | 1/20 | 0.81 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.81 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.81 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.81 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8977555 | 1.00 | CCKBR (0.81) | CCKBRCCKARGABRPGABRDGABRA1 | |
| SCHEMBL7213169 | 0.92 | CCKBR (0.85) | CCKBRCCKARGABRPGABRDGABRA1 | |
| SCHEMBL8977570 | 0.89 | CCKBR (1.00) | CCKBRCCKARGABRPGABRDGABRA1 | |
| SCHEMBL8977565 | 0.89 | CCKBR (1.00) | CCKBRCCKARGABRPGABRDGABRA1 | |
| SCHEMBL9524671 | 0.89 | CCKBR (1.00) | CCKBRCCKARGABRPGABRDGABRA1 | |
| SCHEMBL9524675 | 0.89 | CCKBR (1.00) | CCKBRCCKARGABRPGABRDGABRA1 | |
| SCHEMBL8977576 | 0.89 | CCKBR (0.79) | CCKBRCCKARGABRPGABRDGABRA1 | |
| SCHEMBL8977573 | 0.89 | CCKBR (0.79) | CCKBRCCKARGABRPGABRDGABRA1 | |
| SCHEMBL9867540 | 0.88 | CCKBR (1.00) | CCKBRCCKARGABRPGABRDGABRA1 | |
| SCHEMBL8977579 | 0.88 | CCKAR (1.00) | CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0508724-B1 | Radiopharmaceutical bacteriostats | MERCK FROSST CANADA INC (CA) | 1996-08-07 | — | — | EP | claimed |
| US-5306482-A | Benz(alk or eth)orium chloride | MERCK FROSST CANADA, INC. (CA) | 1994-04-26 | — | — | US | claimed |
| US-5227152-A | Benzalkonium chloride or benzethonium chloride | MERCK FROSST CANADA, INC. (CA) | 1993-07-13 | — | — | US | claimed |
| EP-0508724-B1 | Radiopharmaceutical bacteriostats | MERCK FROSST CANADA INC (CA) | 1996-08-07 | — | — | EP | disclosed |
| EP-0445976-B1 | Gamma emitting, CCK-A antagonists for pancreatic imaging | MERCK & CO INC (US) | 1996-05-01 | — | — | EP | disclosed |
| US-5306482-A | Benz(alk or eth)orium chloride | MERCK FROSST CANADA, INC. (CA) | 1994-04-26 | — | — | US | disclosed |
| US-5227152-A | Benzalkonium chloride or benzethonium chloride | MERCK FROSST CANADA, INC. (CA) | 1993-07-13 | — | — | US | disclosed |
| US-5093105-A | Tc-based, pertechnetate reducing agent, antioxidant, benzalkonium chloride, benzethonium chloride | MERCK FROSST CANADA, INC. (CA) | 1992-03-03 | — | — | US | disclosed |
| EP-0445976-A1 | Gamma emitting, CCK-A antagonists for pancreatic imaging | MERCK & CO. INC. (US) | 1991-09-11 | — | — | EP | disclosed |
| US-4994258-A | Radiolabeled cholecystokinin-A antagonists bind to receptors | MERCK & CO., INC. (US) | 1991-02-19 | — | — | US | disclosed |