SCHEMBL8977568

SCHEMBL8977568

C=C(C(N)=O)C(C)NC(C)C

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.39
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL321949 0.80
SCHEMBL7894760 0.80 TDP1 (0.33) TDP1TSHR
SCHEMBL22034857 0.78 TDP1 (0.38) TDP1TSHR
Chloromethane SCHEMBL16430274 0.76 TDP1 (0.36) TDP1
SCHEMBL11670289 0.76 TDP1 (0.32) TDP1
SCHEMBL6010126 0.76
SCHEMBL6009645 0.76
SCHEMBL3945125 0.76
SCHEMBL11909582 0.75 SLC6A3 (0.39) TDP1
SCHEMBL2830001 0.75 TDP1 (0.35) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0472204-B1 Surface treated materials of excellent adhesion for painting layer, corrosion resistance after painting, and press formability, as well as a method of manufacturing them KOBE STEEL LTD (JP) 1996-04-24 EP claimed
EP-0472204-B1 Surface treated materials of excellent adhesion for painting layer, corrosion resistance after painting, and press formability, as well as a method of manufacturing them KOBE STEEL LTD (JP) 1996-04-24 EP disclosed
US-5169726-A A zinc or iron series plating layer; a (meth)acrylic polymer having repeating units of a (meth)acrylic acid derivative containing an epoxy group KABUSHIKI KAISHA KOBE SEIKO SHO (JP) 1992-12-08 US disclosed
EP-0472204-A2 Surface treated materials of excellent adhesion for painting layer, corrosion resistance after painting, and press formability, as well as a method of manufacturing them KABUSHIKI KAISHA KOBE SEIKO SHO (JP) 1992-02-26 EP disclosed