Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.36 |
| ▸ | CX3CR1 | P49238 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.33 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19206145 | 0.84 | CYP3A4 (0.41) | CYP3A4MAPK1CYP2C9TSHRCXCR2 | |
| SCHEMBL1955903 | 0.83 | CYP3A4 (0.50) | CYP3A4MAPK1CYP2C9TSHRCXCR2 | |
| SCHEMBL27862996 | 0.79 | CYP3A4 (0.37) | CYP3A4MAPK1TSHRCXCR2HSD17B10 | |
| SCHEMBL11053121 | 0.79 | CYP2C9 (0.51) | CYP3A4MAPK1CYP2C9TSHRCXCR2 | |
| SCHEMBL11789072 | 0.78 | CYP2C9 (0.39) | CYP3A4MAPK1CYP2C9TSHRHSD17B10 | |
| SCHEMBL14395756 | 0.77 | DPP4 (0.41) | CYP3A4MAPK1CYP2C9TSHRCXCR2 | |
| SCHEMBL9349986 | 0.75 | CYP3A4 (0.37) | CYP3A4MAPK1CYP2C9TSHRHSD17B10 | |
| SCHEMBL5728040 | 0.74 | TSHR (0.48) | CYP2C9TSHRCXCR2CX3CR1ALDH1A1 | |
| SCHEMBL10422854 | 0.74 | HSD17B10 (0.50) | CYP3A4MAPK1CYP2C9TSHRHSD17B10 | |
| SCHEMBL10424568 | 0.74 | HPGD (0.47) | CYP3A4MAPK1TSHRHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021054432-A1 | METHOD FOR MEASURING TARGET COMPONENT USING ENZYME, AND MEASUREMENT REAGENT | 積水メディカル株式会社 | 2021-03-25 | — | — | WO | claimed |
| US-3954690-A | Removal of sulfuric acid compounds | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-05-04 | — | — | US | claimed |
| WO-2021054432-A1 | METHOD FOR MEASURING TARGET COMPONENT USING ENZYME, AND MEASUREMENT REAGENT | 積水メディカル株式会社 | 2021-03-25 | — | — | WO | disclosed |
| EP-0496993-B1 | Enzymatic process for preparing 7-aminocephalosporanic acid and derivatives | ANTIBIOTICOS SPA (IT) | 1996-05-01 | — | — | EP | disclosed |
| US-5424196-A | Oxidative deamination of Cephalosporin C by immobilized D-aminoacid oxidase (Rhodotorula) and oxygen; deacetylation using immobilized glutaryl-7-aminocephalosporanic acid acylase; water-insoluble and reuseable enzyme supports | ANTIBIOTICOS S.P.A. (IT) | 1995-06-13 | — | — | US | disclosed |
| EP-0496993-A1 | Enzymatic process for preparing 7-aminocephalosporanic acid and derivatives | ANTIBIOTICOS, S.p.A. (IT) | 1992-08-05 | — | — | EP | disclosed |
| US-5126246-A | Measurement of glycerol or fatty acid produced by enzymatic hydrolysis with combination of lipases | TOYO JOZO COMPANY, LTD. (JP) | 1992-06-30 | — | — | US | disclosed |
| US-5047329-A | Method for the measurement of creatine or creatinine and reagents for these measurements | NODA INSTITUTE FOR SCIENTIFIC RESEARCH (JP) | 1991-09-10 | — | — | US | disclosed |
| US-4916078-A | SUPERIMPOSING FORCE ON FLUID FLOW | BOEHRINGER MANNHEIM GMBH (DE) | 1990-04-10 | — | — | US | disclosed |
| US-4898832-A | Process for carrying out analytical determinations and means for carrying out this process | BOEHRINGER MANNHEIM GMBH (DE) | 1990-02-06 | — | — | US | disclosed |
| US-4740465-A | CULTURING BACILLUS | NODA INSTITUTE FOR SCIENTIFIC RESEARCH (JP) | 1988-04-26 | — | — | US | disclosed |
| US-4521519-A | PHOSPHOTUNGSTIC ACID AND MAGNESIUM IONS | BOEHRINGER MANNHEIM GMBH (DE) | 1985-06-04 | — | — | US | disclosed |
| EP-0064665-B1 | PRECIPITATING REAGENT FOR PRE-B-LIPOPROTEINS, METHOD OF PREPARING THE SAME AND ITS USE IN THE DETERMINATION OF HDL CHOLESTEROL | Roche Diagnostics GmbH (DE) | 1985-04-10 | — | — | EP | disclosed |
| EP-0064665-A1 | Precipitating reagent for pre-B-lipoproteins, method of preparing the same and its use in the determination of HDL cholesterol | Roche Diagnostics GmbH (DE) | 1982-11-17 | — | — | EP | disclosed |
| US-4025479-A | Removal of sulfuric acid compounds | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-05-24 | — | — | US | disclosed |
| US-3954690-A | Removal of sulfuric acid compounds | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-05-04 | — | — | US | disclosed |